Mycetoma: Difference between revisions
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=== Microbiology === |
=== Microbiology === |
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* Can be caused either by fungi or filamentous aerobic bacteria |
* Can be caused either by fungi or filamentous aerobic bacteria |
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* Fungal species (eumycotic mycetoma): |
* Fungal species ('''eumycotic mycetoma'''): |
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** Dark grains: |
** Dark grains: |
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*** ''[[Madurella mycetomatis]]'' |
*** ''[[Madurella mycetomatis]]'' |
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*** ''[[Acremonium kiliense]]'' |
*** ''[[Acremonium kiliense]]'' |
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*** ''[[Aspergillus flavus]]'', ''[[Aspergillus nidulans]]'', ''[[Aspergillus hollandicus]]'' |
*** ''[[Aspergillus flavus]]'', ''[[Aspergillus nidulans]]'', ''[[Aspergillus hollandicus]]'' |
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* Aerobic bacteria (actinomycotic mycetoma): |
* Aerobic bacteria ('''actinomycotic mycetoma'''): |
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** ''[[Nocardia brasiliensis]]'' |
** ''[[Nocardia brasiliensis]]'' |
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** ''[[Actinomadura madurae]]'' |
** ''[[Actinomadura madurae]]'' |
Revision as of 16:14, 3 November 2019
- Chronic progressive granulomatous infection of the skin and subcutaneous tissue, usually affecting a single extremity
Background
Microbiology
- Can be caused either by fungi or filamentous aerobic bacteria
- Fungal species (eumycotic mycetoma):
- Dark grains:
- Pale/white grains:
- Pseudallescheria boydii (most common) (Scedosporium)
- Acremonium kiliense
- Aspergillus flavus, Aspergillus nidulans, Aspergillus hollandicus
- Aerobic bacteria (actinomycotic mycetoma):
- Nocardia brasiliensis
- Actinomadura madurae
- Streptomyces somaliensis
- Actinomadura pelletieri (grains are red to pink)
Clinical Presentation
- Clinical triad:
- Localized swelling
- Underlying sinus tract
- Grains and granules (“sulfur granules”) within the sinus tracts
Diagnosis
- Send granules in sterile container
- Gram stain a crushed granule for bacteria, then set up cultures for bacterial and fungal cultures