Pasteurella multocida: Difference between revisions
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Pasteurella multocida
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== Background == |
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* Normal flora of cat and dog mouths |
* Normal flora of cat and dog mouths |
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== Clinical Manifestations == |
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* Can cause SSTI and bacteremia secondary to bites or licks |
* Can cause SSTI and bacteremia secondary to bites or licks |
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== Management == |
== Management == |
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* Susceptible to some beta lactams |
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* First-line antibiotics: [[amoxicillin-clavulanic acid]] 875/125 mg po BID |
* First-line antibiotics: [[amoxicillin-clavulanic acid]] 875/125 mg po BID |
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* Reliable alternatives that can likely be used empirically[[CiteRef::wei2025pa]] |
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* Alternatives: |
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** [[Penicillin VK]] 500 mg po qid |
** [[Penicillin VK]] 500 mg po qid |
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** [[Amoxicillin]] 500 mg po tid |
** [[Amoxicillin]] 500 mg po tid |
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** [[Doxycycline]] 100 mg po bid |
** [[Doxycycline]] 100 mg po bid |
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** [[TMP-SMX]] DS 1 tab po bid |
** [[TMP-SMX]] DS 1 tab po bid |
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{{DISPLAYTITLE:''Pasteurella multocida''}} |
{{DISPLAYTITLE:''Pasteurella multocida''}} |
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Revision as of 14:46, 11 November 2025
Background
- Normal flora of cat and dog mouths
Clinical Manifestations
- Can cause SSTI and bacteremia secondary to bites or licks
Management
- First-line antibiotics: amoxicillin-clavulanic acid 875/125 mg po BID
- Reliable alternatives that can likely be used empirically1
- Penicillin VK 500 mg po qid
- Amoxicillin 500 mg po tid
- Cefuroxime 500 mg po q12h
- Levofloxacin 750 mg po daily
- Moxifloxacin 400 mg po daily
- Doxycycline 100 mg po bid
- TMP-SMX DS 1 tab po bid
- In vitro resistance to cephalexin, cloxacillin, clindamycin, and erythromycin2
References
- ^ Bo Wei, Chang Liu, Jie Zhu, XinYu Zou, Zhenhua Zhang. Pasteurella multocida infection: a differential retrospective study of 482 cases of P. multocida infection in patient of different ages. BMC Infectious Diseases. 2025;25(1). doi:10.1186/s12879-025-10711-1.
- ^ PMID6371440
