Escherichia coli: Difference between revisions
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Escherichia coli
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| + | == Background == |
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| − | * [[Has Gram stain::Gram-negative]] bacillus |
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| + | === Microbiology === |
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| + | * Lactose-fermenting [[Has Gram stain::Gram-negative]] [[Has shape::bacillus]] within the [[Enterobacteriaceae]] |
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* Member of commensal gut flora |
* Member of commensal gut flora |
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| + | * Has multiple '''pathotypes''' |
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| + | ** Extraintestinal pathogenic ''E. coli'' (ExPEC): causes UTI and neonatal meningitis |
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| + | *** Strains that cause neonatal meningitis are more likely to produce K1 capsule and S fimbriae |
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| + | ** Enterotoxigenic ''E. coli'' (ETEC): produces enterotoxins, causes acute watery diarrhea |
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| + | ** Enteropathogenic ''E. coli'' (EPEC): produces localize adherence pilus, causes severe acute watery diarrhea that can become chronic |
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| + | ** Enterhemorrhagic ''E.coli'' (EHEC) and Shiga toxin-producing ''E. coli'' (STEC): produces Shiga toxins, causes watery and bloody diarrhea and can lead to HUS |
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| + | ** Enteroaggregative ''E. coli'' (EAEC): produces adherence factors, causes mucoid diarrhea that can become chronic |
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| + | ** Enteroinvasive ''E. coli'' (EIEC): spreads cell-to-cell, causes watery diarrhea or dysentery |
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| + | ** Diffuse-adhering ''E. coli'' (DAEC): causes diarrhea |
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{{DISPLAYTITLE:''Escherichia coli''}} |
{{DISPLAYTITLE:''Escherichia coli''}} |
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Revision as of 21:17, 13 November 2019
Background
Microbiology
- Lactose-fermenting Gram-negative bacillus within the Enterobacteriaceae
- Member of commensal gut flora
- Has multiple pathotypes
- Extraintestinal pathogenic E. coli (ExPEC): causes UTI and neonatal meningitis
- Strains that cause neonatal meningitis are more likely to produce K1 capsule and S fimbriae
- Enterotoxigenic E. coli (ETEC): produces enterotoxins, causes acute watery diarrhea
- Enteropathogenic E. coli (EPEC): produces localize adherence pilus, causes severe acute watery diarrhea that can become chronic
- Enterhemorrhagic E.coli (EHEC) and Shiga toxin-producing E. coli (STEC): produces Shiga toxins, causes watery and bloody diarrhea and can lead to HUS
- Enteroaggregative E. coli (EAEC): produces adherence factors, causes mucoid diarrhea that can become chronic
- Enteroinvasive E. coli (EIEC): spreads cell-to-cell, causes watery diarrhea or dysentery
- Diffuse-adhering E. coli (DAEC): causes diarrhea
- Extraintestinal pathogenic E. coli (ExPEC): causes UTI and neonatal meningitis
