Giardia lamblia: Difference between revisions
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Giardia lamblia
(Created page with "* A member of the Giardia species that causes intestinal disease in humans and animals {{DISPLAYTITLE:''Giardia lamblia''}} Category:Protozoa Category:Gastrointesti...") |
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− | * A member of the [[Giardia species]] that causes intestinal disease in humans and animals |
+ | * A member of the [[Giardia species]] that causes intestinal disease ('''giardiasis''') in humans and animals |
+ | * Also known as '''beaver fever''' |
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+ | |||
+ | == Microbiology == |
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+ | |||
+ | * Flagellated protozoan that infects the small bowel |
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+ | * Host specificity related to genotype ("assemblage") |
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+ | ** Assemblages A & B infect humans, but also numerous non-human hosts including primates, dogs, cars, cattle, sheep, deer, rodents, horses, and beavers |
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+ | ** Assemblages C & D affect dogs; E affects cattle, goats, sheep, and pigs; F affects cats; G affects rodents; and H affects marine vertebrates |
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+ | * Antigenic variation is determined by the variant-specific surface protein (VSP) |
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+ | ** Replaced every few generations |
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+ | |||
+ | == Life Cycle == |
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+ | |||
+ | * A cyst is ingested via fecal-oral contamination |
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+ | * In the small bowel, the cyst releases two trophozoites (free-living form) via excystation |
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+ | * Trophozoites multiply by binary fission |
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+ | * When they reach the large bowel, they encyst |
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+ | |||
+ | == Epidemiology == |
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+ | |||
+ | * Worldwide distribution |
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+ | * Numerous animal reservoirs, not fully understood how important they are |
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+ | * Cysts can survive several months in cold water |
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+ | |||
{{DISPLAYTITLE:''Giardia lamblia''}} |
{{DISPLAYTITLE:''Giardia lamblia''}} |
Revision as of 21:04, 8 October 2019
- A member of the Giardia species that causes intestinal disease (giardiasis) in humans and animals
- Also known as beaver fever
Microbiology
- Flagellated protozoan that infects the small bowel
- Host specificity related to genotype ("assemblage")
- Assemblages A & B infect humans, but also numerous non-human hosts including primates, dogs, cars, cattle, sheep, deer, rodents, horses, and beavers
- Assemblages C & D affect dogs; E affects cattle, goats, sheep, and pigs; F affects cats; G affects rodents; and H affects marine vertebrates
- Antigenic variation is determined by the variant-specific surface protein (VSP)
- Replaced every few generations
Life Cycle
- A cyst is ingested via fecal-oral contamination
- In the small bowel, the cyst releases two trophozoites (free-living form) via excystation
- Trophozoites multiply by binary fission
- When they reach the large bowel, they encyst
Epidemiology
- Worldwide distribution
- Numerous animal reservoirs, not fully understood how important they are
- Cysts can survive several months in cold water