Giardia lamblia: Difference between revisions
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Giardia lamblia
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* A member of the [[Giardia species]] that causes intestinal disease in humans and animals |
* A member of the [[Giardia species]] that causes intestinal disease ('''giardiasis''') in humans and animals |
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* Also known as '''beaver fever''' |
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== Microbiology == |
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* Flagellated protozoan that infects the small bowel |
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* Host specificity related to genotype ("assemblage") |
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** Assemblages A & B infect humans, but also numerous non-human hosts including primates, dogs, cars, cattle, sheep, deer, rodents, horses, and beavers |
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** Assemblages C & D affect dogs; E affects cattle, goats, sheep, and pigs; F affects cats; G affects rodents; and H affects marine vertebrates |
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* Antigenic variation is determined by the variant-specific surface protein (VSP) |
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** Replaced every few generations |
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== Life Cycle == |
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* A cyst is ingested via fecal-oral contamination |
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* In the small bowel, the cyst releases two trophozoites (free-living form) via excystation |
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* Trophozoites multiply by binary fission |
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* When they reach the large bowel, they encyst |
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== Epidemiology == |
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* Worldwide distribution |
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* Numerous animal reservoirs, not fully understood how important they are |
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* Cysts can survive several months in cold water |
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{{DISPLAYTITLE:''Giardia lamblia''}} |
{{DISPLAYTITLE:''Giardia lamblia''}} |
Revision as of 01:04, 9 October 2019
- A member of the Giardia species that causes intestinal disease (giardiasis) in humans and animals
- Also known as beaver fever
Microbiology
- Flagellated protozoan that infects the small bowel
- Host specificity related to genotype ("assemblage")
- Assemblages A & B infect humans, but also numerous non-human hosts including primates, dogs, cars, cattle, sheep, deer, rodents, horses, and beavers
- Assemblages C & D affect dogs; E affects cattle, goats, sheep, and pigs; F affects cats; G affects rodents; and H affects marine vertebrates
- Antigenic variation is determined by the variant-specific surface protein (VSP)
- Replaced every few generations
Life Cycle
- A cyst is ingested via fecal-oral contamination
- In the small bowel, the cyst releases two trophozoites (free-living form) via excystation
- Trophozoites multiply by binary fission
- When they reach the large bowel, they encyst
Epidemiology
- Worldwide distribution
- Numerous animal reservoirs, not fully understood how important they are
- Cysts can survive several months in cold water