Actinomyces: Difference between revisions

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Actinomyces
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= Actinomyces =
= Microbiology =

== Microbiology ==


* Weakly Gram-positive bacterium that looks fungal under microscopy
* Weakly Gram-positive bacterium that looks fungal under microscopy
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* Spreads by direct invasion through tissue and creating fistulae
* Spreads by direct invasion through tissue and creating fistulae


== Syndromes ==
= Syndromes =


=== Cervicofacial actinomycosis ===
== Cervicofacial actinomycosis ==


* "Lumpy jaw syndrome" with painless jaw mass, trismus, and eventually pain
* "Lumpy jaw syndrome" with painless jaw mass, trismus, and eventually pain
* Most common form, accounting for ~50% of cases
* Most common form, accounting for ~50% of cases


=== Abdominal actinomycosis ===
== Abdominal actinomycosis ==


* Presents as an abdominal mass that fistulizes to skin
* Presents as an abdominal mass that fistulizes to skin


=== Pulmonary actinomycosis ===
== Pulmonary actinomycosis ==


* Presents as a chronic, non-resolving pneumonia or as a lung cancer
* Presents as a chronic, non-resolving pneumonia or as a lung cancer
* Can spread directly to involve heart as well
* Can spread directly to involve heart as well


=== Others ===
== Others ==


* Endocarditis
* Endocarditis


== Management ==
= Management =


* IV penicillin x4-6 weeks then PO penicillin x6-12 months
* IV penicillin x4-6 weeks then PO penicillin x6-12 months
* Alternatives include ceftriaxone, amox/clav
* Alternatives include ceftriaxone, amox/clav

{{DISPLAYTITLE:''Actinomyces'' species}}
[[Category:Bacteria]]

Revision as of 22:42, 14 August 2019

Microbiology

  • Weakly Gram-positive bacterium that looks fungal under microscopy
  • Oral and gut flora
  • Spreads by direct invasion through tissue and creating fistulae

Syndromes

Cervicofacial actinomycosis

  • "Lumpy jaw syndrome" with painless jaw mass, trismus, and eventually pain
  • Most common form, accounting for ~50% of cases

Abdominal actinomycosis

  • Presents as an abdominal mass that fistulizes to skin

Pulmonary actinomycosis

  • Presents as a chronic, non-resolving pneumonia or as a lung cancer
  • Can spread directly to involve heart as well

Others

  • Endocarditis

Management

  • IV penicillin x4-6 weeks then PO penicillin x6-12 months
  • Alternatives include ceftriaxone, amox/clav