Actinomyces: Difference between revisions

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Actinomyces
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== Management ==
== Management ==


* IV penicillin x4-6 weeks then PO penicillin x6-12 months
* IV [[penicillin]] x4-6 weeks then PO [[penicillin]] x6-12 months
* Alternatives include ceftriaxone, amox/clav
* Alternatives include [[ceftriaxone]], amox/clav


{{DISPLAYTITLE:''Actinomyces'' species}}
{{DISPLAYTITLE:''Actinomyces'' species}}

Revision as of 12:11, 16 August 2019

Microbiology

  • Weakly Gram-positive bacterium that looks fungal under microscopy
  • Oral and gut flora
  • Spreads by direct invasion through tissue and creating fistulae

Syndromes

Cervicofacial actinomycosis

  • "Lumpy jaw syndrome" with painless jaw mass, trismus, and eventually pain
  • Most common form, accounting for ~50% of cases

Abdominal actinomycosis

  • Presents as an abdominal mass that fistulizes to skin

Pulmonary actinomycosis

  • Presents as a chronic, non-resolving pneumonia or as a lung cancer
  • Can spread directly to involve heart as well

Others

  • Endocarditis

Management

References

  1. ^  Anna Jeffery-Smith, Caoimhe Nic-Fhogartaigh, Michael Millar. P. Bourbeau. Is the Presence of Actinomyces spp. in Blood Culture Always Significant?. Journal of Clinical Microbiology. 2016;54(4):1137-1139. doi:10.1128/jcm.03074-15.