Valacyclovir: Difference between revisions

From IDWiki
(Created page with "== Background == * Also known as Valtrex == Dosing == * HSV ** Mucocutaneous *** Immunocompetent **** Initial episode: 1 g p.o. twice daily for 7 to 10 days (may be extended) **** Recurrent episode: 1 g po. daily for 5 days **** Suppressive therapy: 500 to 1000 mg p.o. daily *** Immunocompromised **** Episode: 1 g p.o. twice daily for 5 to 10 days **** Suppressive therapy: 500 mg p.o. twice daily ** Orolabial (cold sores) *** Initial episode: 1 g p.o. twice daily...")
 
No edit summary
Line 2: Line 2:


* Also known as Valtrex
* Also known as Valtrex
* Prodrug of [[acyclovir]] but with easier dosing


== Dosing ==
== Dosing ==

Revision as of 14:51, 16 September 2024

Background

  • Also known as Valtrex
  • Prodrug of acyclovir but with easier dosing

Dosing

  • HSV
    • Mucocutaneous
      • Immunocompetent
        • Initial episode: 1 g p.o. twice daily for 7 to 10 days (may be extended)
        • Recurrent episode: 1 g po. daily for 5 days
        • Suppressive therapy: 500 to 1000 mg p.o. daily
      • Immunocompromised
        • Episode: 1 g p.o. twice daily for 5 to 10 days
        • Suppressive therapy: 500 mg p.o. twice daily
    • Orolabial (cold sores)
      • Initial episode: 1 g p.o. twice daily for 7 to 10 days
      • Recurrent episode: 2 g p.o. twice daily for 2 doses
    • Prophylaxis in transplant: 500 mg p.o. twice daily
  • VZV
    • Localized shingles (within 72 hours of onset): 1 g p.o. three times daily for 7 to 10 days
    • Disseminated zoster: 1 g p.o. three times daily to complete 10 to 14 days
    • Opthalmicus: 1 g p.o. three times daily for 7 days
    • Uncomplicated varicella (chickenpox) (within 24 hours of onset): 1 g p.o. three times daily for 5 to 7 days until lesions have crusted
    • Prophylaxis in transplant: 500 mg p.o. twice daily