Amoxicillin-clavulanic acid: Difference between revisions
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==Dosing== |
==Dosing== |
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* Oral: 500 mg/125 mg p.o. three times daily, or 875 mg/125 mg p.o. twice daily |
* Oral: 500 mg/125 mg p.o. three times daily, or 875 mg/125 mg p.o. twice daily |
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* Intravenous: |
* Intravenous: |
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** Usual dose: 1 g (1000 mg/ 200 mg) IV every 8 hours |
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** High dose: 2 g (2000 mg/ 200 mg) IV every 8 to 12 hours |
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=== Renal Dosing === |
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{| class="wikitable" |
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!CrCl (mL/min) |
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!Dose |
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|- |
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! colspan="2" |Oral |
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|- |
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|>30 |
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|875/125 mg p.o. q12h |
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|- |
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|10-29 |
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|500/125 mg p.o. q12h |
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|- |
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|<10 |
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|500/125 mg p.o. q24h |
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|- |
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|Hemodialysis |
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|500/125 mg p.o. q24h (given after dialysis on dialysis days) |
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|- |
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|Peritoneal dialysis |
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|250/125 mg p.o. q12h |
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|- |
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|CRRT |
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|Usual dose |
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|- |
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! colspan="2" |Intravenous |
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|- |
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|>30 |
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|1 g IV q8h |
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|- |
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|10-29 |
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|1 g IV followed by 500 mg IV q12h |
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|- |
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|<10 |
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|1 g IV followed by 500 mg IV q24h |
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|- |
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|Hemodialysis |
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|1 g IV followed by 500 mg IV q24h (given after dialysis on dialysis days) |
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|} |
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[[Category:β-lactams]] |
[[Category:β-lactams]] |
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[[Category:Β-lactamase inhibitors]] |
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Latest revision as of 19:21, 23 June 2023
Dosing
- Oral: 500 mg/125 mg p.o. three times daily, or 875 mg/125 mg p.o. twice daily
- Intravenous:
- Usual dose: 1 g (1000 mg/ 200 mg) IV every 8 hours
- High dose: 2 g (2000 mg/ 200 mg) IV every 8 to 12 hours
Renal Dosing
| CrCl (mL/min) | Dose |
|---|---|
| Oral | |
| >30 | 875/125 mg p.o. q12h |
| 10-29 | 500/125 mg p.o. q12h |
| <10 | 500/125 mg p.o. q24h |
| Hemodialysis | 500/125 mg p.o. q24h (given after dialysis on dialysis days) |
| Peritoneal dialysis | 250/125 mg p.o. q12h |
| CRRT | Usual dose |
| Intravenous | |
| >30 | 1 g IV q8h |
| 10-29 | 1 g IV followed by 500 mg IV q12h |
| <10 | 1 g IV followed by 500 mg IV q24h |
| Hemodialysis | 1 g IV followed by 500 mg IV q24h (given after dialysis on dialysis days) |
