Herpes simplex pneumonitis: Difference between revisions
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* Pathology shows intranuclear inclusion bodies or positive immunohistochemical stain |
* Pathology shows intranuclear inclusion bodies or positive immunohistochemical stain |
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==Investigations |
== Investigations == |
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* CT chest shows one of three patterns: diffuse or multifocal ground-glass opacities, multifocal peribronchial consolidation, or a mixture of both[[CiteRef::chong2010he]] |
* CT chest shows one of three patterns: diffuse or multifocal ground-glass opacities, multifocal peribronchial consolidation, or a mixture of both[[CiteRef::chong2010he]] |
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== Management == |
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* In mechanically ventilated patients with positive HSV PCR, [[acyclovir]] 5 to 10 mg/kg IV q8h for 14 days[[CiteRef::luyt2020ac]][[CiteRef::heimes2020ef]] |
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[[Category:Respiratory infections]] |
[[Category:Respiratory infections]] |
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Latest revision as of 22:09, 12 March 2022
Background
- Pulmonary infection of HSV
- Pathology shows intranuclear inclusion bodies or positive immunohistochemical stain
Investigations
- CT chest shows one of three patterns: diffuse or multifocal ground-glass opacities, multifocal peribronchial consolidation, or a mixture of both1
Management
References
- ^ S Chong, T S Kim, E Y Cho. Herpes simplex virus pneumonia: high-resolution CT findings. The British Journal of Radiology. 2010;83(991):585-589. doi:10.1259/bjr/51409455.
- ^ Charles-Edouard Luyt, Jean-Marie Forel, David Hajage, Samir Jaber, Sophie Cayot-Constantin, Thomas Rimmelé, Elisabeth Coupez, Qin Lu, Mamadou Hassimiou Diallo, Christine Penot-Ragon, Marc Clavel, Carole Schwebel, Jean-François Timsit, Jean-Pierre Bedos, Caroline Hauw-Berlemont, Jérémy Bourenne, Julien Mayaux, Jean-Yves Lefrant, Jean-Paul Mira, Alain Combes, Michel Wolff, Jean Chastre, Laurent Papazian. Acyclovir for Mechanically Ventilated Patients With Herpes Simplex Virus Oropharyngeal Reactivation. JAMA Internal Medicine. 2020;180(2):263. doi:10.1001/jamainternmed.2019.5713.
- ^ Elisabeth Heimes, Michael Baier, Christina Forstner, Sebastian Weis, Michael Bauer, Michael Fritzenwanger, André Scherag, Mathias W. Pletz, Miriam Kesselmeier, Stefan Hagel. Effect of Antiviral Therapy on the Outcome of Mechanically Ventilated Patients With Herpes Simplex Virus Type 1 in BAL Fluid. Chest. 2020;158(5):1867-1875. doi:10.1016/j.chest.2020.06.056.
