Nutritionally variant streptococci: Difference between revisions
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== Management == |
== Management == |
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| − | * Susceptibilities shown below are from |
+ | * Susceptibilities shown below are from several studies[[CiteRef::kanamoto2018an]][[CiteRef::patel2017an]][[CiteRef::mushtaq2016di]] |
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|Penicillin |
|Penicillin |
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| − | |57% |
+ | |14 to 57% |
| − | |82% |
+ | |34 to 82% |
| − | |100% |
+ | |80 to 100% |
|- |
|- |
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|Ampicillin |
|Ampicillin |
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| Line 43: | Line 43: | ||
|- |
|- |
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|Ceftriaxone |
|Ceftriaxone |
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| − | |100% |
+ | |92 to 100% |
| − | |76% |
+ | |22 to 76% |
| − | |100% |
+ | |90 to 100% |
|- |
|- |
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|Ceftazidime |
|Ceftazidime |
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| Line 56: | Line 56: | ||
|100% |
|100% |
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|100% |
|100% |
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| + | |- |
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| + | |Meropenem |
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| + | |72 to 81% |
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| + | |87 to 95% |
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| + | |91% |
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|- |
|- |
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|Gentamicin |
|Gentamicin |
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|18% |
|18% |
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|17% |
|17% |
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| + | |- |
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| + | |Levofloxacin |
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| + | |100% |
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| + | |97 to 100% |
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| + | |92% |
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|- |
|- |
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|Minocycline |
|Minocycline |
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|100% |
|100% |
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|100% |
|100% |
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| − | |83% |
+ | |83 to 100% |
|- |
|- |
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|TMP-SMX |
|TMP-SMX |
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Latest revision as of 15:28, 11 March 2022
Background
- Require pyridoxine (vitamin B6) supplementation to group
- Also called pyridoxal-dependent or stalliting streptococci
Organisms
Clinical Manifestations
- Subacute bacterial endocarditis is the most well-known disease association
Management
| Antibiotic | Abiotrophia defectiva | Granulicatella adiacens | Granulicatella elegans |
|---|---|---|---|
| Penicillin | 14 to 57% | 34 to 82% | 80 to 100% |
| Ampicillin | 86% | 100% | 100% |
| Piperacillin | 0% | 53% | 100% |
| Cefazolin | 29% | 88% | 100% |
| Ceftriaxone | 92 to 100% | 22 to 76% | 90 to 100% |
| Ceftazidime | 0% | 0% | 50% |
| Imipenem | 100% | 100% | 100% |
| Meropenem | 72 to 81% | 87 to 95% | 91% |
| Gentamicin | 0% | 0% | 0% |
| Ciprofloxacin | 100% | 18% | 17% |
| Levofloxacin | 100% | 97 to 100% | 92% |
| Minocycline | 57% | 94% | 100% |
| Vancomycin | 100% | 100% | 83 to 100% |
| TMP-SMX | 14% | 0% | 17% |
References
- ^ Taisei Kanamoto, Shigemi Terakubo, Hideki Nakashima. Antimicrobial Susceptibilities of Oral Isolates of Abiotrophia and Granulicatella According to the Consensus Guidelines for Fastidious Bacteria. Medicines. 2018;5(4):129. doi:10.3390/medicines5040129.
