Renal disease in HIV patients: Difference between revisions

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m (Aidan moved page RNA Human immunodeficiency virus Renal disease to Renal disease in HIV without leaving a redirect)
m (Aidan moved page Renal disease in HIV to Renal disease in HIV patients without leaving a redirect)
 
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= Renal disease in HIV =


== Differential Diagnosis ==
== Differential Diagnosis ==
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== HIV-associated nephropathy (HIVAN) ==
== HIV-associated nephropathy (HIVAN) ==


=== Presentation ===
=== Clinical Manifestations ===


* Proteinuria, mild creatinine elevation, normal-seized echogenic kidneys on renal US
* Proteinuria, mild creatinine elevation, normal-seized echogenic kidneys on renal US
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* Steroids for 8 to 12 weeks
* Steroids for 8 to 12 weeks
* ACEi/ARB as tolerated
* ACEi/ARB as tolerated

[[Category:HIV]]

Latest revision as of 14:21, 13 July 2024

Differential Diagnosis

  • Infection-related
    • HIV-associated nephropathy (HIVAN)
    • Immune complex-mediated glomerular disease
    • Coinfection with hepatitis B or C
  • Treatment-related
    • Tenofovir: Fanconi syndrome
    • Pantamidine, foscarnet, and aminoglycosides: ATN
    • Indinavir, sulfadiazine, and IV acyclovir: tubular obstruction from crystals

HIV-associated nephropathy (HIVAN)

Clinical Manifestations

  • Proteinuria, mild creatinine elevation, normal-seized echogenic kidneys on renal US
  • Usually have a detectable viral load, and decreased CD4 <200
  • Biopsy shows FSGS

Management

  • Treat the HIV with usual therapy
  • Steroids for 8 to 12 weeks
  • ACEi/ARB as tolerated