Desomorphine: Difference between revisions

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* Also called krokodil, krok, Russian magic
* Also called krokodil, krok, Russian magic
* First reported in Russia in 2003
* Injected SC or IV, or taken orally
* Injected SC or IV, or taken orally
* Mechanism of action is mu-opioid receptor agonism
* Mechanism of action is mu-opioid receptor agonism

== Clinical Manifestations ==

=== Intoxication and Withdrawal ===

* Similar to other opioids

=== Skin and Soft Tissue Manifestations ===

* Can cause a green scaly appearance of the skin after injections, often with ulceration of skin, muscle, and cartilage
* Can cause gangrene down to bone, resulting in amputations
* The tissue damage is usually from contamination with paint thinner, lighter fluid, gasoline, lead, zinc, and hydrochloric acid used to prepare the drug


[[Category:Addiction medicine]]
[[Category:Addiction medicine]]

Latest revision as of 19:22, 2 July 2021

Background

  • Also called krokodil, krok, Russian magic
  • First reported in Russia in 2003
  • Injected SC or IV, or taken orally
  • Mechanism of action is mu-opioid receptor agonism

Clinical Manifestations

Intoxication and Withdrawal

  • Similar to other opioids

Skin and Soft Tissue Manifestations

  • Can cause a green scaly appearance of the skin after injections, often with ulceration of skin, muscle, and cartilage
  • Can cause gangrene down to bone, resulting in amputations
  • The tissue damage is usually from contamination with paint thinner, lighter fluid, gasoline, lead, zinc, and hydrochloric acid used to prepare the drug