Desomorphine: Difference between revisions
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(Created page with "== Background == * Also called krokodil, krok, Russian magic * Injected SC or IV, or taken orally * Mechanism of action is mu-opioid receptor agonism Category:Addiction me...") |
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* Also called krokodil, krok, Russian magic |
* Also called krokodil, krok, Russian magic |
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| + | * First reported in Russia in 2003 |
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* Injected SC or IV, or taken orally |
* Injected SC or IV, or taken orally |
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* Mechanism of action is mu-opioid receptor agonism |
* Mechanism of action is mu-opioid receptor agonism |
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| + | |||
| + | == Clinical Manifestations == |
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| + | |||
| + | === Intoxication and Withdrawal === |
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| + | |||
| + | * Similar to other opioids |
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| + | |||
| + | === Skin and Soft Tissue Manifestations === |
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| + | |||
| + | * Can cause a green scaly appearance of the skin after injections, often with ulceration of skin, muscle, and cartilage |
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| + | * Can cause gangrene down to bone, resulting in amputations |
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| + | * The tissue damage is usually from contamination with paint thinner, lighter fluid, gasoline, lead, zinc, and hydrochloric acid used to prepare the drug |
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[[Category:Addiction medicine]] |
[[Category:Addiction medicine]] |
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Latest revision as of 15:22, 2 July 2021
Background
- Also called krokodil, krok, Russian magic
- First reported in Russia in 2003
- Injected SC or IV, or taken orally
- Mechanism of action is mu-opioid receptor agonism
Clinical Manifestations
Intoxication and Withdrawal
- Similar to other opioids
Skin and Soft Tissue Manifestations
- Can cause a green scaly appearance of the skin after injections, often with ulceration of skin, muscle, and cartilage
- Can cause gangrene down to bone, resulting in amputations
- The tissue damage is usually from contamination with paint thinner, lighter fluid, gasoline, lead, zinc, and hydrochloric acid used to prepare the drug
