WBC scan: Difference between revisions
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* Radiolabelled white blood cell scintography |
* Radiolabelled white blood cell scintography |
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* Extremely useful in distinguishing post-operative changes (where WBCs rarely accumulate) from post-surgical infection[[CiteRef::signore2018cl]] |
* Extremely useful in distinguishing post-operative changes (where WBCs rarely accumulate) from post-surgical infection[[CiteRef::signore2018cl]] |
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* Several options exist |
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** Indium-111-labelled: good for acute infections, including intraabdominal infections and osteomyelitis, though maybe less sensitive for chronic infections and spinal osteomyelitis |
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*** Good for osteomyelitis when combined with [[bone scan]] |
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*** This is probably the workhorse radiotracer |
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** Technetium-99m-labelled: higher spatial resolution and lower radiation dose |
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*** Because it's faster with lower radiation, it is preferred in pediatrics |
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*** Better for bowel imaging because it doesn't routinely accumulate in the bowels in the way that indium does |
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*** Not used with [[Bone scan|bone scans]] |
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** SPECT: used to improved anatomic localization |
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== Further Reading == |
== Further Reading == |
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Latest revision as of 14:42, 3 October 2025
- Radiolabelled white blood cell scintography
- Extremely useful in distinguishing post-operative changes (where WBCs rarely accumulate) from post-surgical infection1
- Several options exist
- Indium-111-labelled: good for acute infections, including intraabdominal infections and osteomyelitis, though maybe less sensitive for chronic infections and spinal osteomyelitis
- Good for osteomyelitis when combined with bone scan
- This is probably the workhorse radiotracer
- Technetium-99m-labelled: higher spatial resolution and lower radiation dose
- Because it's faster with lower radiation, it is preferred in pediatrics
- Better for bowel imaging because it doesn't routinely accumulate in the bowels in the way that indium does
- Not used with bone scans
- SPECT: used to improved anatomic localization
- Indium-111-labelled: good for acute infections, including intraabdominal infections and osteomyelitis, though maybe less sensitive for chronic infections and spinal osteomyelitis
Further Reading
- Clinical indications, image acquisition and data interpretation for white blood cells and anti-granulocyte monoclonal antibody scintigraphy: an EANM procedural guideline. Eur J Nucl Med Mol Imaging. 2018;45(10):1816–1831. doi: 10.1007/s00259-018-4052-x
References
- ^ A. Signore, F. Jamar, O. Israel, J. Buscombe, J. Martin-Comin, E. Lazzeri. Clinical indications, image acquisition and data interpretation for white blood cells and anti-granulocyte monoclonal antibody scintigraphy: an EANM procedural guideline. European Journal of Nuclear Medicine and Molecular Imaging. 2018;45(10):1816-1831. doi:10.1007/s00259-018-4052-x.
