Tuberculous adenitis: Difference between revisions

Latest revision as of 13:44, 25 November 2020

Paradoxial reaction including paradoxical upgrading reaction
Presents with enlarging lymphadenopathy during or sometimes after treatment
Occurs in 25% of adenitis
Likely represents a reaction to an antigenic stimulus in poorly-cleared disease
In post-treatment paradoxical reactions, need to differentiate from relapse
About half will be PCR positive, 20% will be AFB positive, but none are culture positive
90% resolve spontaneously
Steroids used commonly

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-== Clinical Manifestations ==
+==Clinical Manifestations==
-=== Paradoxical Reactions ===
+===Paradoxical Reactions===
-* Paradoxial reaction including paradoxical upgrading reaction
+*Paradoxial reaction including paradoxical upgrading reaction
+*Presents with enlarging lymphadenopathy during or sometimes after treatment
-* Occurs in 25% of adenitis
+*Occurs in 25% of adenitis
-** Usually during treatment but can occur after treatment
-* Likely reaction to antigenic stimulus in poorly-cleared disease
+*Likely represents a reaction to an antigenic stimulus in poorly-cleared disease
-* In post-treatment paradoxical reactions, need to differentiate from relapse
+*In post-treatment paradoxical reactions, need to differentiate from relapse
-* About half will be PCR positive, 20% will be AFB positive, but none are culture positive
+*About half will be PCR positive, 20% will be AFB positive, but none are culture positive
+*90% resolve spontaneously
+*Steroids used commonly
 [[Category:Tuberculosis]]