Congenital parvovirus: Difference between revisions

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== Background ==
{| class="wikitable"
!Trimester
!Transmission to Fetus
|-
|first
| rowspan="2" |33%
|-
|second
|-
|third
|0%
|-
|overall
|9%
|}

== Clinical Presentation ==

* Hydrops fetalis in utero
* Heart failure
* Myocarditis

==Diagnosis==
==Diagnosis==
===Serology===
===Serology===

* IgM antibody is detectable by 10 to 12 days after infection (peak viremia), and persists for up to 3 months
* IgG antibody is detectable about 2 weeks after infection and persists for life
*IgM antibody is detectable by 10 to 12 days after infection (peak viremia), and persists for up to 3 months
*IgG antibody is detectable about 2 weeks after infection and persists for life


{| class="wikitable"
{| class="wikitable"
! IgM !! IgG !! Interpretation
!IgM!!IgG!!Interpretation
|-
|-
| || || Susceptible
|−||−||Susceptible
|-
|-
| + || || Acute infection
| +||−||Acute infection
|-
|-
| || + || Remote infection, at least 3-4 months ago
|−||+||Remote infection, at least 3-4 months ago
|-
|-
| + || + || Recent infection, within 2-3 months
| +||+||Recent infection, within 2-3 months
|}
|}


[[Category:DNA viruses]]
[[Category:Congenital infections]]
[[Category:Congenital infections]]
[[Category:Pediatrics]]

Latest revision as of 00:18, 22 September 2020

Background

Trimester Transmission to Fetus
first 33%
second
third 0%
overall 9%

Clinical Presentation

  • Hydrops fetalis in utero
  • Heart failure
  • Myocarditis

Diagnosis

Serology

  • IgM antibody is detectable by 10 to 12 days after infection (peak viremia), and persists for up to 3 months
  • IgG antibody is detectable about 2 weeks after infection and persists for life
IgM IgG Interpretation
Susceptible
+ Acute infection
+ Remote infection, at least 3-4 months ago
+ + Recent infection, within 2-3 months