Rhodotorula: Difference between revisions
From IDWiki
Rhodotorula
m (Text replacement - "([Ss])olid-organ" to "$1olid organ") |
m (Text replacement - " species}}" to "}}") |
||
| (3 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
== Background == |
== Background == |
||
=== Microbiology === |
=== Microbiology === |
||
* A genus of basidiomycetous [[ |
* A genus of basidiomycetous [[Shape::yeast]] |
||
* Primary human pathogens include: |
* Primary human pathogens include: |
||
** ''Rhodotorula mucilaginosa'' (most common isolate) |
** ''Rhodotorula mucilaginosa'' (most common isolate) |
||
| Line 7: | Line 7: | ||
** ''Rhodotorula minuta'' |
** ''Rhodotorula minuta'' |
||
* In culture, have characteristic pink yeast colonies, with a capsule seen on microscopy |
* In culture, have characteristic pink yeast colonies, with a capsule seen on microscopy |
||
* [[Urease |
* Urease [[Urease::positive]] |
||
=== Epidemiology === |
=== Epidemiology === |
||
| Line 27: | Line 27: | ||
* Rhodotorula infection. A systematic review of 128 cases from literature. ''Rev Iberoam Micol''. 2008;25(3):135-40. pmid: [https://www.ncbi.nlm.nih.gov/pubmed/18785780 18785780] |
* Rhodotorula infection. A systematic review of 128 cases from literature. ''Rev Iberoam Micol''. 2008;25(3):135-40. pmid: [https://www.ncbi.nlm.nih.gov/pubmed/18785780 18785780] |
||
{{DISPLAYTITLE:''Rhodotorula'' |
{{DISPLAYTITLE:''Rhodotorula''}} |
||
[[Category:Yeasts]] |
[[Category:Yeasts]] |
||
Latest revision as of 19:05, 19 February 2022
Background
Microbiology
- A genus of basidiomycetous yeast
- Primary human pathogens include:
- Rhodotorula mucilaginosa (most common isolate)
- Rhodotorula glutinis
- Rhodotorula minuta
- In culture, have characteristic pink yeast colonies, with a capsule seen on microscopy
- Urease positive
Epidemiology
- Rare
- More common in immunocompromised patients, especially hematologic malignancy, but also solid organ malignancy, transplant, and advanced HIV
Clinical Manifestations
- Most common presentation is with a fungemia
- Mostly central line infection, but also fungemia without focus, and, rarely, endocarditis
- Can cause central line infections in immunocompetent patients
- Endophthalmitis, keratitis, and corneal infection
- Peritoneal-dialysis associated peritonitis
- Rare meningitis and ventriculitis
Management
- Mostly treated with amphotericin B, but also 5-fluorocytosine, ketoconazole, and miconazole
Further Reading
- Rhodotorula infection. A systematic review of 128 cases from literature. Rev Iberoam Micol. 2008;25(3):135-40. pmid: 18785780
