Congenital HSV: Difference between revisions
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** Do not send superficial swabs for PCR during the first 24 hours of life, since this can generate false positive from superficial contamination from the birthing process |
** Do not send superficial swabs for PCR during the first 24 hours of life, since this can generate false positive from superficial contamination from the birthing process |
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[[Category:Congenital infections]] |
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[[Category:Viruses]] |
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[[Category:Infectious diseases]] |
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Latest revision as of 16:22, 20 September 2020
Background
Clinical Manifestations
- Characterized by microcephaly, hydrocephalus, chorioretinitis, and skin findings
- Rash may be vesicular, bullous, or cicatricial
- Rash either present at birth or within a few days
- Two thirds have severe CNS involvement
Diagnosis
- Most commonly made with PCR of lesions or CSF
- Do not send superficial swabs for PCR during the first 24 hours of life, since this can generate false positive from superficial contamination from the birthing process
