Nutritionally variant streptococci: Difference between revisions
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* [[Subacute bacterial endocarditis]] is the most well-known disease association |
* [[Subacute bacterial endocarditis]] is the most well-known disease association |
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| + | == Management == |
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| + | |||
| + | * Susceptibilities shown below are from several studies[[CiteRef::kanamoto2018an]][[CiteRef::patel2017an]][[CiteRef::mushtaq2016di]] |
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| + | |||
| + | {| class="wikitable" |
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| + | !Antibiotic |
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| + | ![[Abiotrophia defectiva]] |
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| + | ![[Granulicatella adiacens]] |
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| + | ![[Granulicatella elegans]] |
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| + | |- |
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| + | |Penicillin |
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| + | |14 to 57% |
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| + | |34 to 82% |
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| + | |80 to 100% |
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| + | |- |
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| + | |Ampicillin |
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| + | |86% |
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| + | |100% |
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| + | |100% |
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| + | |- |
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| + | |Piperacillin |
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| + | |0% |
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| + | |53% |
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| + | |100% |
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| + | |- |
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| + | |Cefazolin |
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| + | |29% |
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| + | |88% |
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| + | |100% |
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| + | |- |
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| + | |Ceftriaxone |
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| + | |92 to 100% |
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| + | |22 to 76% |
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| + | |90 to 100% |
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| + | |- |
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| + | |Ceftazidime |
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| + | |0% |
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| + | |0% |
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| + | |50% |
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| + | |- |
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| + | |Imipenem |
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| + | |100% |
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| + | |100% |
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| + | |100% |
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| + | |- |
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| + | |Meropenem |
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| + | |72 to 81% |
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| + | |87 to 95% |
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| + | |91% |
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| + | |- |
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| + | |Gentamicin |
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| + | |0% |
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| + | |0% |
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| + | |0% |
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| + | |- |
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| + | |Ciprofloxacin |
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| + | |100% |
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| + | |18% |
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| + | |17% |
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| + | |- |
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| + | |Levofloxacin |
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| + | |100% |
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| + | |97 to 100% |
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| + | |92% |
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| + | |- |
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| + | |Minocycline |
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| + | |57% |
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| + | |94% |
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| + | |100% |
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| + | |- |
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| + | |Vancomycin |
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| + | |100% |
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| + | |100% |
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| + | |83 to 100% |
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| + | |- |
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| + | |TMP-SMX |
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| + | |14% |
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| + | |0% |
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| + | |17% |
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| + | |} |
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[[Category:Gram-positive cocci]] |
[[Category:Gram-positive cocci]] |
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Latest revision as of 15:28, 11 March 2022
Background
- Require pyridoxine (vitamin B6) supplementation to group
- Also called pyridoxal-dependent or stalliting streptococci
Organisms
Clinical Manifestations
- Subacute bacterial endocarditis is the most well-known disease association
Management
| Antibiotic | Abiotrophia defectiva | Granulicatella adiacens | Granulicatella elegans |
|---|---|---|---|
| Penicillin | 14 to 57% | 34 to 82% | 80 to 100% |
| Ampicillin | 86% | 100% | 100% |
| Piperacillin | 0% | 53% | 100% |
| Cefazolin | 29% | 88% | 100% |
| Ceftriaxone | 92 to 100% | 22 to 76% | 90 to 100% |
| Ceftazidime | 0% | 0% | 50% |
| Imipenem | 100% | 100% | 100% |
| Meropenem | 72 to 81% | 87 to 95% | 91% |
| Gentamicin | 0% | 0% | 0% |
| Ciprofloxacin | 100% | 18% | 17% |
| Levofloxacin | 100% | 97 to 100% | 92% |
| Minocycline | 57% | 94% | 100% |
| Vancomycin | 100% | 100% | 83 to 100% |
| TMP-SMX | 14% | 0% | 17% |
References
- ^ Taisei Kanamoto, Shigemi Terakubo, Hideki Nakashima. Antimicrobial Susceptibilities of Oral Isolates of Abiotrophia and Granulicatella According to the Consensus Guidelines for Fastidious Bacteria. Medicines. 2018;5(4):129. doi:10.3390/medicines5040129.
