Aerococcus: Difference between revisions

Latest revision as of 14:10, 21 June 2024

Gram-positive coccus
Notable species
- Aerococcus urinae, which causes urinary tract infections
- Aerococcus sanguinicola, causes UTIs, but sometimes a contaminant
- Aerococcus viridans, often a contaminant
Presumed resistance in vivo to TMP-SMX, even though it may appear susceptible in vitro
- It can acquire folate from the host's urine, counteracting the antibiotic

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 == Microbiology ==
-* [[Has Gram stain::Gram-positive]] [[Cellular shape::coccus]]
+* [[Stain::Gram-positive]] [[Shape::coccus]]
 * Notable species
-** ''A. urinae'', which causes urinary tract infections
+** [[Aerococcus urinae]], which causes urinary tract infections
-** ''A. sanguinicola'', often a contaminant
+** [[Aerococcus sanguinicola]], causes UTIs, but sometimes a contaminant
-** ''A. viridans'', often a contaminant
+** [[Aerococcus viridans]], often a contaminant
 * Presumed resistance ''in vivo'' to [[TMP-SMX]], even though it may appear susceptible ''in vitro''
 ** It can acquire folate from the host's urine, counteracting the antibiotic
-== Clinical Presentation ==
+== Clinical Manifestations ==
 * ''A. urinae'' causes [[UTI]] and [[endocarditis]] (often following UTI in older men)
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 == Management ==
-* Penicillin ± aminoglycoside
+* [[Penicillin]] or [[ampicillin]]
+* ± [[aminoglycoside]] (for synergy, based on in vitro studies)
+* Can be susceptible to [[ceftriaxone]], though MICs are higher than for [[penicillin]]
+== Further Reading ==
-{{DISPLAYTITLE:''Aerococcus'' species}}
+* ''Aerococcus'': an increasingly acknowledged human pathogen. ''Clin Microbiol Infect''. 2016 Jan;22(1):22-27. doi: [https://doi.org/10.1016/j.cmi.2015.09.026 10.1016/j.cmi.2015.09.026]. PMID: [https://pubmed.ncbi.nlm.nih.gov/26454061/ 26454061].{{DISPLAYTITLE:''Aerococcus''}}
 [[Category:Gram-positive cocci]]