Actinomycetes: Difference between revisions

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== Background ==
==Background==
* A genetically unrelated group of [[Has Gram stain::Gram-positive]] [[Has shape::bacillus|bacilli]]
* Filamentous soil bacteria
* More commonly seen in fungal cultures
* Typically ''not'' acid-fast


*Filamentous, mostly branching [[Stain::Gram-positive]] [[Shape::bacillus|bacilli]]
== Organisms ==
*The order Actinomycetales includes the aerobic actinomycetes
* Partially acid-fast (cell wall contains mycolic acid)
**Actinomycetales also include [[Corynebacterium]] (non-branching, non-acid-fast), [[Mycobacterium]] (non-branching, fully acid-fast), and [[Tropheryma whipplei]]
** [[Nocardia species]]
*Environmental organisms found in soil
** [[Rhodococcus species]]: red colonies, associated with horses
*More commonly seen in fungal cultures
** [[Gordonia species]]
*Typically ''not'' acid-fast, though some are partially acid-fast
** [[Tsukamurella species]]
** [[Corynebacterium species]]
* Not partially acid-fast (cell wall does not contain mycolic acid)
** [[Streptomyces species]]: common contaminant
** [[Actinomadura species]]
** [[Dermatophilus species]]
** [[Nodardiopsis species]]
** [[Oerskovia species]]


==Organisms==
{| class="wikitable"
!Genus
!Infections
|-
! colspan="2" |Partially acid-fast (cell wall contains mycolic acid)
|-
|[[Nocardia]]
|[[mycetoma]], lymphocutaneous infections, skin abscesses; in immunocompromised hosts, invasive pulmonary and disseminated infections
|-
|[[Rhodococcus]]
|pulmonary infections, bacteremia, skin and wound infections, UTIs, endophthalmitis, peritonitis, [[CLABSI]], [[abscess]] in prostate, spleen, thyroid, kidney, or brain, osteomyelitis; associated with horses
|-
|[[Gordonia]]
|skin infections, chronic pulmonary disease, [[CLABSI]], wound infections, bacteremia
|-
|[[Tsukamurella]]
|peritonitis, [[CLABSI]], skin infection
|-
! colspan="2" |Not partially acid-fast (cell wall does not contain mycolic acid)
|-
|[[Streptomyces]]
|commonly contaminant; inoculation skin infection including [[mycetoma]]
|-
|[[Actinomadura]]
|inoculation skin infection including [[mycetoma]]
|-
|[[Dermatophilus]]
|inoculation skin infection from insects or thorns
|-
|[[Nodardiopsis]]
|
|-
|[[Oerskovia]]
|
|}<br />
[[Category:Gram-positive bacilli]]
[[Category:Gram-positive bacilli]]
[[Category:Infectious diseases]]

Latest revision as of 16:59, 25 January 2022

Background

  • Filamentous, mostly branching Gram-positive bacilli
  • The order Actinomycetales includes the aerobic actinomycetes
  • Environmental organisms found in soil
  • More commonly seen in fungal cultures
  • Typically not acid-fast, though some are partially acid-fast

Organisms

Genus Infections
Partially acid-fast (cell wall contains mycolic acid)
Nocardia mycetoma, lymphocutaneous infections, skin abscesses; in immunocompromised hosts, invasive pulmonary and disseminated infections
Rhodococcus pulmonary infections, bacteremia, skin and wound infections, UTIs, endophthalmitis, peritonitis, CLABSI, abscess in prostate, spleen, thyroid, kidney, or brain, osteomyelitis; associated with horses
Gordonia skin infections, chronic pulmonary disease, CLABSI, wound infections, bacteremia
Tsukamurella peritonitis, CLABSI, skin infection
Not partially acid-fast (cell wall does not contain mycolic acid)
Streptomyces commonly contaminant; inoculation skin infection including mycetoma
Actinomadura inoculation skin infection including mycetoma
Dermatophilus inoculation skin infection from insects or thorns
Nodardiopsis
Oerskovia