Galactomannan: Difference between revisions

Latest revision as of 17:22, 10 March 2023

Quantitative analysis of galactomannan levels in either bronchoalveolar lavage or blood that is used to diagnose invasive aspergillosis

Galactomannan is a component of the cell wall of Aspergillus that is released when the organism is actively dividing

Usual cuttoff is 0.5, but the higher it is, the more likely it is to be true positive
Bronchoalveolar lavage more sensitive than serum
False-positives in piperacillin-tazobactam, amoxicillin-clavulanic acid, Penicillium (Talaromyces), Histoplasma, Fusarium, Paecilomyces, possibly Nocardia

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+*Quantitative analysis of galactomannan levels in either bronchoalveolar lavage or blood that is used to diagnose invasive aspergillosis
-= Galactomannan =
-== Definition ==
+==Pathophysiology==
+*Galactomannan is a component of the cell wall of [[Aspergillus]] that is released when the organism is actively dividing
-* Quantitative analysis of galactomannan levels in either bronchoalveolar lavage or blood that is used to diagnose invasive aspergillosis
+==Interpretation==
-== Pathophysiology ==
+*Usual cuttoff is 0.5, but the higher it is, the more likely it is to be true positive
-* Galactomannan is a component of the cell wall of ''Aspergillus'' species that is released when the organism is actively dividing
+*Bronchoalveolar lavage more sensitive than serum
+*False-positives in [[piperacillin-tazobactam]], [[amoxicillin-clavulanic acid]], [[Penicillium]] ([[Talaromyces]]), [[Histoplasma]], [[Fusarium]], [[Paecilomyces]], possibly [[Nocardia]]
+[[Category:Diagnostics]]
-== Interpretation ==
-* Bronchoalveolar lavage more sensitive than serum
-* False-positives in pip/tazo, amox/clav, Penicillium spp., Histoplasma spp.