Dobutamine: Difference between revisions
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==Background== |
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== Classification == |
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*Synthetic catecholamine with B1 and B2 agonist activity, causing inotropy and chronotropy and mild vasodilation |
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===Indications=== |
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*Systolic heart failure causing cardiogenic shock, especially if bradycardic |
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*Also used for cardiac stress testing |
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=== Pharmacokinetics and Pharmacodynamics === |
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== Starting == |
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==Dosing== |
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== Half-life == |
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==Safety== |
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=== Adverse Drug Reactions === |
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*Tachycardia |
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*Hypertension or hypotension |
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*Increased ventricular response in atrial fibrillation |
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*Ventricular arrhythmias |
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*Can worsen myocardial ischemia |
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*Eosinophilic myocarditis |
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[[Category:Cardiology]] |
[[Category:Cardiology]] |
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[[Category:Medications]] |
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Latest revision as of 15:11, 14 April 2021
Background
- Synthetic catecholamine with B1 and B2 agonist activity, causing inotropy and chronotropy and mild vasodilation
Indications
- Systolic heart failure causing cardiogenic shock, especially if bradycardic
- Also used for cardiac stress testing
Pharmacokinetics and Pharmacodynamics
- Half-life is a few minutes
Dosing
- Start at 2 to 20 mcg/kg/min (max 40)
Safety
Adverse Drug Reactions
- Tachycardia
- Hypertension or hypotension
- Increased ventricular response in atrial fibrillation
- Ventricular arrhythmias
- Can worsen myocardial ischemia
- Eosinophilic myocarditis
