Bony metastases: Difference between revisions
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== Differential Diagnosis == |
== Differential Diagnosis == |
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* Osteoblastic lesions |
* Osteoblastic (sclerotic) lesions, with deposition of new bone |
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** |
**[[Prostate cancer]] |
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** Carcinoid |
** [[Carcinoid tumour]] |
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** Small cell lung cancer |
** [[Small cell lung cancer]] |
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** Hodgkin lymphoma |
** [[Hodgkin lymphoma]] |
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** [[Medulloblastoma]] |
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* Osteolytic lesions |
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* Osteolytic lesions, with destruction of normal bone |
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** |
**[[Renal cell carcinoma]] |
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** Melanoma |
** [[Melanoma]] |
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** Multiple myeloma |
** [[Multiple myeloma]] |
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** Thyroid cancer |
** [[Thyroid cancer]] |
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** Non-Hodgkin lymphoma |
** [[Non-Hodgkin lymphoma]] |
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** [[Non-small cell lung cancer]] |
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** [[Langerhans cell histiocytosis]] |
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** [[Lytic bone lesion|Non-malignant causes of lytic bone lesions]] |
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* Mixed lesions |
* Mixed lesions |
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** |
**[[Breast cancer]], though it is predominantly osteolytic |
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** Colorectal and other gastrointestinal cancers |
** [[Colorectal cancer]] and other gastrointestinal cancers |
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** Squamous cell |
** [[Squamous cell cancer]] |
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== Management == |
== Management == |
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* Denosumab at high dose |
* [[Denosumab]] at high dose |
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* [[Bisphosphonate]] |
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* Bisphosphonates |
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== Further Reading == |
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* Bone Metastases: An Overview. ''Oncol Rev''. 2017 Mar 3; 11(1): 321. doi: [https://doi.org/10.4081/oncol.2017.321 10.4081/oncol.2017.321] |
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[[Category:Oncology]] |
[[Category:Oncology]] |
Latest revision as of 20:25, 18 May 2023
Differential Diagnosis
- Osteoblastic (sclerotic) lesions, with deposition of new bone
- Osteolytic lesions, with destruction of normal bone
- Mixed lesions
- Breast cancer, though it is predominantly osteolytic
- Colorectal cancer and other gastrointestinal cancers
- Squamous cell cancer
Management
- Denosumab at high dose
- Bisphosphonate
Further Reading
- Bone Metastases: An Overview. Oncol Rev. 2017 Mar 3; 11(1): 321. doi: 10.4081/oncol.2017.321