Asthma-COPD overlap syndrome: Difference between revisions

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== Differentiating Asthma and COPD ==
== Differentiating [[Asthma]] and [[COPD]] ==


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! Asthma
! Asthma
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=== Required Criteria ===
=== Required Criteria ===


# Diagnosis of COPD based on risk factors, history, and spirometry
# Diagnosis of [[COPD]] based on risk factors, history, and spirometry
# History of asthma, either as a past history or as current symptoms and spirometry consistent with asthma
# History of asthma, either as a past history or as current symptoms and spirometry consistent with asthma
# Spirometry showing post-bronchodilator fixed FEV1/FVC <0.7
# Spirometry showing post-bronchodilator fixed FEV1/FVC <0.7

Latest revision as of 15:49, 21 October 2021

Differentiating Asthma and COPD

Asthma COPD
Age of onset <40 years >40 years
Smoking Not causal >10 pack-years
Sputum Infrequent Often
Allergies Often Infrequent
Symptoms Intermittent and variable Persistent
Course Stable, with exacerbations Progressive, with exacerbations
Spirometry Often normal Never normalizes

Diagnostic Criteria (CTS 2017)

Required Criteria

  1. Diagnosis of COPD based on risk factors, history, and spirometry
  2. History of asthma, either as a past history or as current symptoms and spirometry consistent with asthma
  3. Spirometry showing post-bronchodilator fixed FEV1/FVC <0.7

Supportive Criteria

  • Bronchodilator improvement in FEV1 of 12% and 200 mL
  • Sputum eosinophils >3%
  • Blood eosinophils > 300 cell/uL

Management

  • Same non-pharmacologic/preventative management as both COPD and asthma
  • For puffers, try to use ones that are good in both
    • Don't use LABA monotherapy (b/c not good in asthma)
    • Don't use inhaled steroid alone (b/c not good in COPD)
  • Puffers:
    • SABA prn
    • Next add ICS/LABA
    • Next add LAMA