Immunization of people with asplenia and hyposplenia: Difference between revisions

Latest revision as of 14:18, 17 August 2022

Can receive all routine vaccines, including live vaccines
Try to complete vaccines at least 2 weeks before splenectomy, or wait at least 2 weeks after vaccination to start
Vaccines specifically recommended in asplenia or hyposplenia:
- Haemophilus influenzae type b (Hib), one dose
- Neisseria meningitidis:
  - Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart followed by a booster every 5 years
  - 4CMenB, two doses 4 weeks apart
- Streptococcus pneumoniae:
  - Pneu-C-13, one dose with a booster at 5 years. Must wait at least 1 year after Pneu-P-23.
  - Pneu-P-23, one dose. Must wait at least 8 weeks after Pneu-C-13.
- Influenza (annually)
- If transfusion-dependent: hepatitis A and B vaccines
Should also have pill-in-pocket broad-spectrum oral antibiotics to be taken in case of fever

Sample schedule for vaccination before planned splenectomy
Week -10	Week -2	Week 0	Ongoing
Men-C-ACYW-135	Men-C-ACYW-135	splenectomy	Men-C-ACYW-135 booster every 5 years
4CMenB	4CMenB
Pneu-C-13	Pneu-P-23		Pneu-C-13 booster at 5 years
Hib
influenza, if appropriate season			annual influenza vaccination

@@ Line 1: / Line 1: @@
-* Can receive all routine vaccines, including live vaccines
+*Can receive all routine vaccines, including live vaccines
+*Try to complete vaccines at least 2 weeks before splenectomy, or wait at least 2 weeks after vaccination to start
-* Vaccines specifically recommended in asplenia or hyposplenia:
+*Vaccines specifically recommended in asplenia or hyposplenia:
-** ''Haemophilus influenzae'' type b (Hib)
+**''Haemophilus influenzae'' type b (Hib), one dose
-** ''Neisseria meningitidis'': quadrivalent Men-C-ACYW and either 4CMenB or MenB-fHBP
+**''Neisseria meningitidis'':
-** ''Streptococcus pneumoniae'': Pneu-C-13 followed by Pneu-P-23
+***Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart followed by a booster every 5 years
-** Influenza (annually)
+***4CMenB, two doses 4 weeks apart
-** If transfusion-dependent: hepatitis A and B vaccines
+**''Streptococcus pneumoniae'':
-* Should also have pill-in-pocket broad-spectrum oral antibiotics to be taken in case of fever
+***Pneu-C-13, one dose with a booster at 5 years. Must wait at least 1 year after Pneu-P-23.
+***Pneu-P-23, one dose. Must wait at least 8 weeks after Pneu-C-13.
+**Influenza (annually)
+**If transfusion-dependent: hepatitis A and B vaccines
+*Should also have pill-in-pocket broad-spectrum oral antibiotics to be taken in case of fever
+{| class="wikitable"
+|+Sample schedule for vaccination before planned splenectomy
+!Week -10
+!Week -2
+!Week 0
+!Ongoing
+|-
+|Men-C-ACYW-135
+|Men-C-ACYW-135
+| rowspan="5" |splenectomy
+|Men-C-ACYW-135 booster every 5 years
+|-
+|4CMenB
+|4CMenB
+|
+|-
+|Pneu-C-13
+|Pneu-P-23
+|Pneu-C-13 booster at 5 years
+|-
+|Hib
+|
+|
+|-
+| colspan="2" |influenza, if appropriate season
+|annual influenza vaccination
+|}
+== Further Reading ==
+* [https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-3-vaccination-specific-populations/page-7-immunization-persons-with-chronic-diseases.html#p3c6a2 Canadian Immunization Guide: Asplenia or hyposplenia]
 [[Category:Immunocompromised hosts‏‎]]