Atovaquone-proguanil: Difference between revisions

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(Created page with "* Combination of atovaquone and proguanil (typically 250 mg-100 mg per tablet) * Used as an antimalarial Category:Antiparasitics")
 
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* Combination of [[atovaquone]] and [[proguanil]] (typically 250 mg-100 mg per tablet)
* Combination of [[atovaquone]] and [[proguanil]] (typically 250 mg-100 mg per tablet, or 62.5 mg-25 mg for a pediatric tablet)
* Used as an antimalarial
* Used as an antimalarial

== Dosing ==

* Treatment: 1000 mg/400 mg (4 tablets) p.o. once daily for 3 days
* Prophylaxis: 250 mg/100 mg (1 tablet) p.o. once daily, from 1 to 2 days before arrival to 7 days after return

=== Pediatric ===

* Treatment:
** 5 to 8 kg: 125 mg/50 mg (2 pediatric tablets) once daily for 3 days
** 9 to 10 kg: 187.5 mg/75 mg (3 pediatric tablets) once daily for 3 days
** 11 to 20 kg: 250 mg/100 mg (1 adult tablet) once daily for 3 days
** 21 to 30 kg: 500 mg/200 mg (2 adult tablets) once daily for 3 days
** 31 to 40 kg: 750 mg/300 mg (3 adult tablets) once daily for 3 days
** >40 kg: 1000 mg/400 mg (4 adult tablets) once daily for 3 days


[[Category:Antiparasitics]]
[[Category:Antiparasitics]]

Latest revision as of 05:01, 11 March 2022

  • Combination of atovaquone and proguanil (typically 250 mg-100 mg per tablet, or 62.5 mg-25 mg for a pediatric tablet)
  • Used as an antimalarial

Dosing

  • Treatment: 1000 mg/400 mg (4 tablets) p.o. once daily for 3 days
  • Prophylaxis: 250 mg/100 mg (1 tablet) p.o. once daily, from 1 to 2 days before arrival to 7 days after return

Pediatric

  • Treatment:
    • 5 to 8 kg: 125 mg/50 mg (2 pediatric tablets) once daily for 3 days
    • 9 to 10 kg: 187.5 mg/75 mg (3 pediatric tablets) once daily for 3 days
    • 11 to 20 kg: 250 mg/100 mg (1 adult tablet) once daily for 3 days
    • 21 to 30 kg: 500 mg/200 mg (2 adult tablets) once daily for 3 days
    • 31 to 40 kg: 750 mg/300 mg (3 adult tablets) once daily for 3 days
    • >40 kg: 1000 mg/400 mg (4 adult tablets) once daily for 3 days