Single-tablet regimens for HIV: Difference between revisions
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#REDIRECT [[HIV medications#Single-Tablet Regimens]] |
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See also [[HIV treatment]] |
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{| class="wikitable" |
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! Brand name |
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! NRTIs |
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! Non-NRTI |
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! Notes |
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|- |
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| Triumeq |
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| [[abacavir]] / [[lamivudine]] |
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| [[dolutegravir]] (INI) |
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| Highest barrier to resistance. Need to test for HLA-B5701 allele before starting. Avoid in hepatitis B coinfection. |
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|- |
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| Atripla |
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| [[tenofovir disoproxil fumarate]] / [[emtricitabine]] |
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| [[efavirenz]] |
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| Older regimen. Neuropsychiatric symptoms, possibly including suicide. |
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|- |
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| Complera |
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| [[tenofovir disoproxil fumarate]] / [[emtricitabine]] |
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| [[rilpivirine]] |
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| Avoid with viral loads (>100,000) or low CD4 (<200). Pill must be taken with food (>400kcal) and without PPIs. |
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|- |
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| Stribild |
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| [[tenofovir disoproxil fumarate]] / [[emtricitabine]] |
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| [[elvitegravir]]/[[cobicistat]] (INI) |
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| Includes a P450 inhibitor to boost elvitegravir levels, with resultant drug-drug interactions. Avoid if CrCl <70. |
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|- |
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| Genvoya |
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| [[tenofovir alafenamide]] / [[emtricitabine]] |
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| [[elvitegravir]]/[[cobicistat]] (INI) |
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| See Stribild, above. |
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|- |
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| Biktarvy |
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| [[tenofovir alafenamide]] / [[emtricitabine]] |
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| [[bictegravir]] (INI) |
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| |
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|} |
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[[Category:HIV]] |
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[[Category:Antivirals]] |
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Latest revision as of 22:23, 4 February 2020
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