Single-tablet regimens for HIV: Difference between revisions

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#REDIRECT [[HIV medications#Single-Tablet Regimens]]
See also [[HIV treatment]]

{| class="wikitable"
! Brand name
! NRTIs
! Non-NRTI
! Notes
|-
| Triumeq
| abacavir / lamivudine
| dolutegravir (INI)
| Highest barrier to resistance. Need to test for HLA-B5701 allele before starting. Avoid in hepatitis B coinfection.
|-
| Atripla
| tenofovir disoproxil / emtricitabine
| efavirenz
| Older regimen. Neuropsychiatric symptoms, possibly including suicide.
|-
| Complera
| tenofovir disoproxil / emtricitabine
| rilpivirine
| Avoid with viral loads (>100,000) or low CD4 (<200). Pill must be taken with food (>400kcal) and without PPIs.
|-
| Stribild
| tenofovir disoproxil / emtricitabine
| elvitegravir/cobicistat (INI)
| Includes a P450 inhibitor to boost elvitegravir levels, with resultant drug-drug interactions. Avoid if CrCl <70.
|-
| Genvoya
| tenofovir alafenamide / emtricitabine
| elvitegravir/cobicistat (INI)
| See Stribild, above.
|-
| Biktarvy
| tenofovir alafenamide / emtricitabine
| bictegravir (INI)
|
|}

[[Category:HIV]]
[[Category:Antivirals]]

Latest revision as of 22:23, 4 February 2020

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