Inadvertent breast milk exposure: Difference between revisions

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* Women often pump breast milk for neonates in hospital, and mix-ups occasionally happen
* Women often pump breast milk for neonates in hospital, and mix-ups occasionally happen
* Risk of infection is low, but includes [[Hepatitis B virus|hepatitis B]], [[Human immunodeficiency virus|HIV]], and [[Human T-lymphotropic virus|HTLV]]
* Risk of infection is low, but includes [[Hepatitis B virus|hepatitis B]], [[Human immunodeficiency virus|HIV]], and [[Human T-lymphotropic virus|HTLV]]

== Investigations ==
* From donor mother, send the following:
** HBsAg and HIV serology, STAT
** HCV and HTLV serology
** CMV serology (if the recipient baby is less than 32 weeks old)
* If the donor mother is positive for any of the above, also test the recipient's mother


== Management ==
== Management ==
* Inform infection control, nurse manager, etc.
* Investigations as above, and management as below
{| class="wikitable"
{| class="wikitable"
! Donor mother !! Recipient mother !! Suggested management
! Donor mother !! Recipient mother !! Suggested management
Line 30: Line 39:
| HIV positive || Continue standard prophylactic therapy
| HIV positive || Continue standard prophylactic therapy
|}
|}

* If given, HBIG should be given within 24 hours and vaccine within 7 days
* If given, HIV prophylaxis should be started within 1 to 2 hours of exposure, but can be started up to 48 hours later


[[Category:Infection_prevention_and_control]]
[[Category:Infection_prevention_and_control]]

Latest revision as of 03:02, 13 November 2019

  • Women often pump breast milk for neonates in hospital, and mix-ups occasionally happen
  • Risk of infection is low, but includes hepatitis B, HIV, and HTLV

Investigations

  • From donor mother, send the following:
    • HBsAg and HIV serology, STAT
    • HCV and HTLV serology
    • CMV serology (if the recipient baby is less than 32 weeks old)
  • If the donor mother is positive for any of the above, also test the recipient's mother

Management

  • Inform infection control, nurse manager, etc.
  • Investigations as above, and management as below
Donor mother Recipient mother Suggested management
Hepatitis B
HBsAg negative HBsAg negative Routine immunization for hepatitis B
HBsAg positive Administer hepatitis B vaccine and immune globulin (HBIG), if not yet given
HBsAg positive HBsAg negative Administer hepatitis B vaccine, if not yet given, and HBIG
HBsAg positive Administer hepatitis B vaccine and HBIG, if not yet given
HIV
HIV negative HIV negative Routine care
HIV positive Continue standard prophylactic therapy
HIV positive HIV negative Could consider zidovudine in high-risk situations, though no routine recommendation
HIV positive Continue standard prophylactic therapy
  • If given, HBIG should be given within 24 hours and vaccine within 7 days
  • If given, HIV prophylaxis should be started within 1 to 2 hours of exposure, but can be started up to 48 hours later