Vibrio parahaemolyticus: Difference between revisions
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Vibrio parahaemolyticus
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== Microbiology == |
== Microbiology == |
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* Halophilic (salt-loving) marine pleomorphic Gram-negative rod that causes foodborne diarrhea |
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== Pathophysiology == |
== Pathophysiology == |
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* Has the capacity to produce an enterotoxin that causes small bowel inflammation |
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** Two hemolysins, thermostable direct hemolysin (TDH) and TGH-related hemolysin (TRH) |
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* Strains without TDH or TRH are usually mild |
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* Likely has a different mechanism of action thatn *V. cholera* for causing diarrhea |
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== Epidemiology == |
== Epidemiology == |
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* Major cause of acute diarrhea in Japan, but also found in east Asia and southern US |
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* Ubiquitous in coastal waters, especially in warmer seasons |
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* Generally acquired by consumption of raw or undercooked seafood, especially raw oysters |
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* Serotype O3:K6 is an important cause of outbreaks, and is the current pandemic strain |
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== Clinical |
== Clinical Manifestations == |
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* Causes acute diarrhea, ranging from mild watery diarrhea to dysentery |
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* Usually, cramping and abdominal pain with low-grade fever and headache |
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* Rarely can cause soft tissue infections and bacteremia |
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== Management == |
== Management == |
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* Usually self-limited |
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* Can use [[doxycycline]] or [[fluoroquinolone]] to shorten the duration of diarrhea |
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{{DISPLAYTITLE:''Vibrio parahaemolyticus''}} |
{{DISPLAYTITLE:''Vibrio parahaemolyticus''}} |
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Latest revision as of 10:56, 2 August 2020
Microbiology
- Halophilic (salt-loving) marine pleomorphic Gram-negative rod that causes foodborne diarrhea
Pathophysiology
- Has the capacity to produce an enterotoxin that causes small bowel inflammation
- Two hemolysins, thermostable direct hemolysin (TDH) and TGH-related hemolysin (TRH)
- Strains without TDH or TRH are usually mild
- Likely has a different mechanism of action thatn *V. cholera* for causing diarrhea
Epidemiology
- Major cause of acute diarrhea in Japan, but also found in east Asia and southern US
- Ubiquitous in coastal waters, especially in warmer seasons
- Generally acquired by consumption of raw or undercooked seafood, especially raw oysters
- Serotype O3:K6 is an important cause of outbreaks, and is the current pandemic strain
Clinical Manifestations
- Causes acute diarrhea, ranging from mild watery diarrhea to dysentery
- Usually, cramping and abdominal pain with low-grade fever and headache
- Rarely can cause soft tissue infections and bacteremia
Management
- Usually self-limited
- Can use doxycycline or fluoroquinolone to shorten the duration of diarrhea
