Bacterial meningitis (IDSA 2004): Difference between revisions
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+ | ==Table 4: Empiric Treatment== |
+ | {| class="wikitable" |
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− | {| |
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− | ! |
+ | !Population |
− | ! |
+ | !Common pathogens |
− | ! |
+ | !Antimicrobial therapy |
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− | + | ! colspan="3" |Age |
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− | | |
+ | |<1 month |
− | | |
+ | |[[Group B streptococcus]], [[Escherichia coli]], [[Listeria]], [[Klebsiella]] |
− | | |
+ | |amp + cefotax, or<br />amp + AG |
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|- |
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− | | |
+ | |1-23 months |
+ | |[[Streptococcus pneumoniae]], [[Neisseria meningitidis]], [[Group B streptococcus]], [[Haemophilus influenzae]], [[Escherichia coli]] |
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− | | S.pneumo, N.mening, GBS, H.flu, E.coli |
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− | | |
+ | |vanco + 3G ceph |
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|- |
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− | | |
+ | |2-50 years |
+ | |[[Neisseria meningitidis]], [[Streptococcus pneumoniae]] |
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− | | N.mening, S.pneumo |
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− | | |
+ | |vanco + 3G ceph |
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− | | |
+ | |>50 years |
+ | |[[Streptococcus pneumoniae]], [[Neisseria meningitidis]], [[Listeria]], [[Gram-negative bacilli]] |
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− | | S.pneumo, N.mining, Listeria, GNBs |
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− | | |
+ | |vanco + 3G ceph + amp |
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− | + | ! colspan="3" |Head trauma |
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− | | |
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− | | |
+ | |Basilar skull fracture |
+ | |[[Streptococcus pneumoniae]], [[Haemophilus influenzae]], [[GAS]] |
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− | | S.pneumo, H.flu, GAS |
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− | | |
+ | |vanco + 3G ceph |
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− | | |
+ | |Penetrating trauma |
+ | |[[Staphylococcus aureus]], [[coagulase-negative staphylococci]], [[Gram-negative bacilli]] |
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− | | Staph.aureus, CoNS, GNBs |
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− | | |
+ | |vanco + cefep, or<br />vanco + ceftaz, or<br />vanco + mero |
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− | | |
+ | |Post-neurosurgery |
+ | |[[Gram-negative bacilli]], [[Staphylococcus aureus]], [[coagulase-negative staphylococci]] |
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− | | GNBs, Staph.aureus, CoNS |
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− | | |
+ | |vanco + cefep, or<br />vanco + ceftaz, or<br />vanco + mero |
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− | | |
+ | |CSF shunt |
+ | |[[Coagulase-negative staphylococci]], [[Staphylococcus aureus]], [[Gram-negative bacilli]], [[Cutibacterium acnes]] |
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− | | CoNS, Staph,aureus, GNBs, P.acnes |
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− | | |
+ | |vanco + cefep, or<br />vanco + ceftaz, or<br />vanco + mero |
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Latest revision as of 15:51, 2 August 2020
Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM, Whitley RJ. Practice guidelines for the management of bacterial meningitis. Clin Infect Dis. 2004 Nov 1;39(9):1267-84. Epub 2004 Oct 6. doi: 10.1086/425368