Bunyavirales

• Order of negative-sense, single-stranded RNA viruses

Family	Virus	Vector	Reservoirs	Distribution	Clinical Features
Arenaviridae	Argentine hemorrhagic fever virus	none	rodents
	Lassa fever virus	none	rodents
Hantaviridae	Hantavirus	none	small rodents	worldwide	fever, shock, AKI, pulmonary edema
Nairoviridae	Crimean-Congo hemorrhagic fever virus	Hyalomma ticks	small mammals, including hares	former Soviet Union, Middle East, and Africa	severe hemorrhagic fever
Peribunyaviridae	California encephalitis virus	Aedes triseriatus	chipmunks	northern US, Canada (mostly Jamestown canyon virus)	meningoencephalitis, seizures, cerebral edema
	La Crosse encephalitis virus
	Jamestown Canyon virus
	Snowshoe hare virus
	Bwamba fever virus	mosquitoes	donkeys
	Oropouche virus	Culicoides paraensis biting midge	birds, sloths, monkeys	Brazil, Peru, Panama, and Trinidad and Tobago	fever, hemorrhage
Phenuiviridae	Heartland virus	Amblyomma americanum ticks		midwestern and southern US	fever, headache, cough, confusion, myalgias, multiorgan failure, thrombocytopenia
	Rift Valley fever virus	Aedes mcintoshi mosquitoes		sub-Saharan Africa	acute fever, retinitis, hemorrhagic fever, encephalitis
	Sand fly fever viruses	Phlebotomus sand flies		Mediterranean	asymptomatic, febrile illness, or meningoencephalitis
	Severe fever with thrombocytopenia syndrome virus	Haemophysalis longicornis, Ixodes nipponensis, and Amblyomma testudinarium ticks		central and eastern China, South Korea, western Japan	fever, multiorgan failure, bleeding diathesis