Doxycycline

• Tetracycline antibiotic
• Usual dosing 100 mg po BID
• Counsel on high risk of sun sensitivity and pill esophagitis
• Generally avoid using in pregnant women and children less than 8 years of age due to bone and tooth staining
  • However, can often tolerate short courses up to 5 days without issue
• Achieves only low concentrations in the urine, so generally not recommended for UTIs
• Can treat: Actinomyces, Bacillary angiomatosis, Bartonella henselae, Borrelia miyamotoi, Brucella melitensis, Burkholderia mallei, Chlamydia trachomatis, Cutibacterium acnes, Enterococcus, Francisella tularensis, Legionella, Leptospira, Lymphogranuloma venereum, Mycoplasma genitalium, Pelvic inflammatory disease, Plasmodium, Rickettsia, Rickettsia africae, Rickettsia akari, Rickettsia conorii, Rickettsia prowazekii, Rickettsia rickettsii, Rickettsia typhi, Rickettsioses, Rickettsioses, Southern tick-associated rash illness, Stenotrophomonas maltophilia, Tick-borne relapsing fever, Treponema pallidum pallidum, Yersinia enterocolitica, Yersinia pestis