Immunization of people with asplenia and hyposplenia: Difference between revisions

Latest revision as of 14:18, 17 August 2022

Can receive all routine vaccines, including live vaccines
Try to complete vaccines at least 2 weeks before splenectomy, or wait at least 2 weeks after vaccination to start
Vaccines specifically recommended in asplenia or hyposplenia:
- Haemophilus influenzae type b (Hib), one dose
- Neisseria meningitidis:
  - Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart followed by a booster every 5 years
  - 4CMenB, two doses 4 weeks apart
- Streptococcus pneumoniae:
  - Pneu-C-13, one dose with a booster at 5 years. Must wait at least 1 year after Pneu-P-23.
  - Pneu-P-23, one dose. Must wait at least 8 weeks after Pneu-C-13.
- Influenza (annually)
- If transfusion-dependent: hepatitis A and B vaccines
Should also have pill-in-pocket broad-spectrum oral antibiotics to be taken in case of fever

Sample schedule for vaccination before planned splenectomy
Week -10	Week -2	Week 0	Ongoing
Men-C-ACYW-135	Men-C-ACYW-135	splenectomy	Men-C-ACYW-135 booster every 5 years
4CMenB	4CMenB
Pneu-C-13	Pneu-P-23		Pneu-C-13 booster at 5 years
Hib
influenza, if appropriate season			annual influenza vaccination

@@ Line 4: / Line 4: @@
 **''Haemophilus influenzae'' type b (Hib), one dose
 **''Neisseria meningitidis'':
-***Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart
+***Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart followed by a booster every 5 years
 ***4CMenB, two doses 4 weeks apart
-**''Streptococcus pneumoniae'': Pneu-C-13, one dose, followed in 8 weeks by Pneu-P-23, one dose
+**''Streptococcus pneumoniae'':
+***Pneu-C-13, one dose with a booster at 5 years. Must wait at least 1 year after Pneu-P-23.
+***Pneu-P-23, one dose. Must wait at least 8 weeks after Pneu-C-13.
 **Influenza (annually)
 **If transfusion-dependent: hepatitis A and B vaccines
@@ Line 16: / Line 18: @@
 !Week -2
 !Week 0
+!Ongoing
 |-
 |Men-C-ACYW-135
-CMenB
-Pneu-C-13
-Hib
 |Men-C-ACYW-135
+| rowspan="5" |splenectomy
-CMenB
+|Men-C-ACYW-135 booster every 5 years
-Pneu-P-23
+|-
-| rowspan="2" |splenectomy
+|4CMenB
+|4CMenB
+|
+|-
+|Pneu-C-13
+|Pneu-P-23
+|Pneu-C-13 booster at 5 years
+|-
+|Hib
+|
+|
 |-
 | colspan="2" |influenza, if appropriate season
+|annual influenza vaccination
 |}
+== Further Reading ==
+* [https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-3-vaccination-specific-populations/page-7-immunization-persons-with-chronic-diseases.html#p3c6a2 Canadian Immunization Guide: Asplenia or hyposplenia]
 [[Category:Immunocompromised hosts‏‎]]
 [[Category:Vaccination]]