Antimicrobial stewardship program: Difference between revisions
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* Monitoring and surveillance |
* Monitoring and surveillance |
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* Reporting and feedback |
* Reporting and feedback |
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== Possible Interventions == |
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* Preauthorization |
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* Prospective audit and feedback |
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* Didactic educational activities, including lectures and pamphlets |
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* Facility-specific clinical practice guidelines for common syndromes |
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* Reducing use of antibiotics with increased risk of [[C. difficile infection]] |
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* Prescriber-led review, including antibiotics time-outs and stop orders |
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* Computerized clinical decision-making support at the time of prescribing |
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* PK monitoring and adjustment of [[aminoglycosides]] and [[vancomycin]] |
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* Alternative dosing of β-lactams |
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* Interventions to increase the use of oral antibiotics for initial therapy as well as timely transition from IV to oral antibiotics |
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* Interventions to reduce the duration of antibiotics to shortest effective duration |
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* Allergy assessments and penicillin skin testing for patients with reported [[β-lactam allergy]] |
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* Development of stratified antibiograms (e.g. by location or age) |
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* Selective and cascade reporting of antimicrobial susceptibility |
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* Rapid viral testing for respiratory pathogens to reduce the use of inappropriate antibiotics |
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* Rapid diagnostic testing on blood specimens |
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* Serial [[procalcitonin]] in ICU patients |
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=== Recommended Against === |
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* Cycling antibiotics |
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== Further Reading == |
== Further Reading == |
Revision as of 17:41, 31 July 2022
Background
- Program to ensure that antimicrobials are used appropriately, in order to improve patient outcomes
Core Elements
- Senior hospital management leadership towards antimicrobial stewardship
- Accountability and responsibilities
- Available expertise on infection management
- Education and practical training
- Other actions aiming at responsible antimicrobial use
- Monitoring and surveillance
- Reporting and feedback
Possible Interventions
- Preauthorization
- Prospective audit and feedback
- Didactic educational activities, including lectures and pamphlets
- Facility-specific clinical practice guidelines for common syndromes
- Reducing use of antibiotics with increased risk of C. difficile infection
- Prescriber-led review, including antibiotics time-outs and stop orders
- Computerized clinical decision-making support at the time of prescribing
- PK monitoring and adjustment of aminoglycosides and vancomycin
- Alternative dosing of β-lactams
- Interventions to increase the use of oral antibiotics for initial therapy as well as timely transition from IV to oral antibiotics
- Interventions to reduce the duration of antibiotics to shortest effective duration
- Allergy assessments and penicillin skin testing for patients with reported β-lactam allergy
- Development of stratified antibiograms (e.g. by location or age)
- Selective and cascade reporting of antimicrobial susceptibility
- Rapid viral testing for respiratory pathogens to reduce the use of inappropriate antibiotics
- Rapid diagnostic testing on blood specimens
- Serial procalcitonin in ICU patients
Recommended Against
- Cycling antibiotics
Further Reading
- How to start an antimicrobial stewardship programme in a hospital. Clin Microbiol Infect. 2019;26(4):447-453. doi: 10.1016/j.cmi.2019.08.007
- Implementing an Antibiotic Stewardship Program: Guidelines by the IDSA and the SHEA. Clin Infect Dis. 2016;62(10):e51-e77. doi: 10.1093/cid/ciw118
- IDSA and the SHEA Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship. Clin Infect Dis. 2007;44:159-77. doi: 10.1086/510393