Rheumatoid arthritis: Difference between revisions
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== Background == |
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* Seropositive inflammatory arthritis |
* Seropositive inflammatory arthritis |
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=== Initial === |
=== Initial === |
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* Methotrexate |
* [[Methotrexate]] |
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* Biologics |
* Biologics |
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** Anti-TNF: adalimumab |
** [[Tumour necrosis factor-α inhibitors|Anti-TNF]]: [[adalimumab]] |
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** T-cell costimulatory inhibitor: abatacept |
** T-cell costimulatory inhibitor: [[abatacept]] |
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** IL-6 antagonist: tocilizumab |
** IL-6 antagonist: [[tocilizumab]] |
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** IL-1 antagonist: anakinra |
** IL-1 antagonist: [[anakinra]] |
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** B-cell depleting agents: rituximab |
** B-cell depleting agents: [[rituximab]] |
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** JAK1/2/3 inhibitor: tofacitinib |
** JAK1/2/3 inhibitor: [[tofacitinib]] |
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=== Chronic === |
=== Chronic === |
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* Vaccination |
* Vaccination |
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** Can give dead vaccines: |
** Can give dead vaccines: influenza, pneumococcus, HBV |
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** Can give live zoster vaccine with methotrexate but not biologics |
** Can give live zoster vaccine with [[methotrexate]] but not biologics |
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** Avoid other live vaccines in both methotrexate and biologicals |
** Avoid other live vaccines in both [[methotrexate]] and biologicals |
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[[Category:Rheumatology]] |
[[Category:Rheumatology]] |
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Latest revision as of 00:56, 17 March 2022
Background
- Seropositive inflammatory arthritis
Management
Initial
- Methotrexate
- Biologics
- Anti-TNF: adalimumab
- T-cell costimulatory inhibitor: abatacept
- IL-6 antagonist: tocilizumab
- IL-1 antagonist: anakinra
- B-cell depleting agents: rituximab
- JAK1/2/3 inhibitor: tofacitinib
Chronic
- Vaccination
- Can give dead vaccines: influenza, pneumococcus, HBV
- Can give live zoster vaccine with methotrexate but not biologics
- Avoid other live vaccines in both methotrexate and biologicals
