Abatacept: Difference between revisions
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Revision as of 00:54, 17 March 2022
- Small-molecule inhibitor of T cell activation
- Formed of extracellular domain of the cytotoxic T lymphocyte-associated antigen 4 linked to the Fc portion of human IgG1
- Decreases T cell activation
- Indications include RA and JRA
- Infectious complications include upper respiratory tract infections, and reports of pneumonia, sepsis, aspergillosis, sinusitis, candidiasis, bronchitis, cellulitis, HSV, and VZV
