Nutritionally variant streptococci: Difference between revisions
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* [[Subacute bacterial endocarditis]] is the most well-known disease association |
* [[Subacute bacterial endocarditis]] is the most well-known disease association |
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== Management == |
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* Susceptibilities shown below are from several studies[[CiteRef::kanamoto2018an]][[CiteRef::patel2017an]][[CiteRef::mushtaq2016di]] |
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{| class="wikitable" |
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!Antibiotic |
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![[Abiotrophia defectiva]] |
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![[Granulicatella adiacens]] |
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![[Granulicatella elegans]] |
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|- |
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|Penicillin |
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|14 to 57% |
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|34 to 82% |
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|80 to 100% |
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|- |
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|Ampicillin |
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|86% |
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|100% |
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|100% |
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|- |
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|Piperacillin |
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|0% |
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|53% |
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|100% |
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|- |
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|Cefazolin |
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|29% |
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|88% |
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|100% |
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|- |
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|Ceftriaxone |
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|92 to 100% |
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|22 to 76% |
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|90 to 100% |
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|- |
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|Ceftazidime |
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|0% |
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|0% |
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|50% |
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|- |
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|Imipenem |
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|100% |
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|100% |
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|100% |
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|- |
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|Meropenem |
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|72 to 81% |
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|87 to 95% |
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|91% |
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|- |
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|Gentamicin |
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|0% |
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|0% |
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|0% |
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|- |
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|Ciprofloxacin |
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|100% |
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|18% |
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|17% |
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|- |
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|Levofloxacin |
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|100% |
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|97 to 100% |
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|92% |
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|- |
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|Minocycline |
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|57% |
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|94% |
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|100% |
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|- |
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|Vancomycin |
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|100% |
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|100% |
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|83 to 100% |
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|- |
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|TMP-SMX |
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|14% |
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|0% |
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|17% |
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|} |
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[[Category:Gram-positive cocci]] |
[[Category:Gram-positive cocci]] |
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Latest revision as of 19:28, 11 March 2022
Background
- Require pyridoxine (vitamin B6) supplementation to group
- Also called pyridoxal-dependent or stalliting streptococci
Organisms
Clinical Manifestations
- Subacute bacterial endocarditis is the most well-known disease association
Management
| Antibiotic | Abiotrophia defectiva | Granulicatella adiacens | Granulicatella elegans |
|---|---|---|---|
| Penicillin | 14 to 57% | 34 to 82% | 80 to 100% |
| Ampicillin | 86% | 100% | 100% |
| Piperacillin | 0% | 53% | 100% |
| Cefazolin | 29% | 88% | 100% |
| Ceftriaxone | 92 to 100% | 22 to 76% | 90 to 100% |
| Ceftazidime | 0% | 0% | 50% |
| Imipenem | 100% | 100% | 100% |
| Meropenem | 72 to 81% | 87 to 95% | 91% |
| Gentamicin | 0% | 0% | 0% |
| Ciprofloxacin | 100% | 18% | 17% |
| Levofloxacin | 100% | 97 to 100% | 92% |
| Minocycline | 57% | 94% | 100% |
| Vancomycin | 100% | 100% | 83 to 100% |
| TMP-SMX | 14% | 0% | 17% |
References
- ^ Taisei Kanamoto, Shigemi Terakubo, Hideki Nakashima. Antimicrobial Susceptibilities of Oral Isolates of Abiotrophia and Granulicatella According to the Consensus Guidelines for Fastidious Bacteria. Medicines. 2018;5(4):129. doi:10.3390/medicines5040129.
