Rhodotorula: Difference between revisions
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Rhodotorula
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== Background == |
== Background == |
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=== Microbiology === |
=== Microbiology === |
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* A genus of basidiomycetous yeast |
* A genus of basidiomycetous [[Shape::yeast]] |
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* Primary human pathogens include: |
* Primary human pathogens include: |
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** ''Rhodotorula mucilaginosa'' (most common isolate) |
** ''Rhodotorula mucilaginosa'' (most common isolate) |
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** ''Rhodotorula glutinis'' |
** ''Rhodotorula glutinis'' |
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** ''Rhodotorula minuta'' |
** ''Rhodotorula minuta'' |
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* In culture, have characteristic pink yeast colonies, with a capsule seen on microscopy |
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* Urease [[Urease::positive]] |
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=== Epidemiology === |
=== Epidemiology === |
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* Rare |
* Rare |
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* More common in immunocompromised patients, especially hematologic malignancy, but also solid |
* More common in immunocompromised patients, especially hematologic malignancy, but also solid organ malignancy, transplant, and advanced HIV |
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== Clinical |
== Clinical Manifestations == |
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* Most common presentation is with a [[Causes::fungemia]] |
* Most common presentation is with a [[Causes::fungemia]] |
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** Mostly [[Causes::central line infection]], but also fungemia without focus, and, rarely, [[Causes::endocarditis]] |
** Mostly [[Causes::central line infection]], but also fungemia without focus, and, rarely, [[Causes::endocarditis]] |
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* Rhodotorula infection. A systematic review of 128 cases from literature. ''Rev Iberoam Micol''. 2008;25(3):135-40. pmid: [https://www.ncbi.nlm.nih.gov/pubmed/18785780 18785780] |
* Rhodotorula infection. A systematic review of 128 cases from literature. ''Rev Iberoam Micol''. 2008;25(3):135-40. pmid: [https://www.ncbi.nlm.nih.gov/pubmed/18785780 18785780] |
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{{DISPLAYTITLE:''Rhodotorula'' |
{{DISPLAYTITLE:''Rhodotorula''}} |
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[[Category:Yeasts]] |
[[Category:Yeasts]] |
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Latest revision as of 19:05, 19 February 2022
Background
Microbiology
- A genus of basidiomycetous yeast
- Primary human pathogens include:
- Rhodotorula mucilaginosa (most common isolate)
- Rhodotorula glutinis
- Rhodotorula minuta
- In culture, have characteristic pink yeast colonies, with a capsule seen on microscopy
- Urease positive
Epidemiology
- Rare
- More common in immunocompromised patients, especially hematologic malignancy, but also solid organ malignancy, transplant, and advanced HIV
Clinical Manifestations
- Most common presentation is with a fungemia
- Mostly central line infection, but also fungemia without focus, and, rarely, endocarditis
- Can cause central line infections in immunocompetent patients
- Endophthalmitis, keratitis, and corneal infection
- Peritoneal-dialysis associated peritonitis
- Rare meningitis and ventriculitis
Management
- Mostly treated with amphotericin B, but also 5-fluorocytosine, ketoconazole, and miconazole
Further Reading
- Rhodotorula infection. A systematic review of 128 cases from literature. Rev Iberoam Micol. 2008;25(3):135-40. pmid: 18785780
