Siderophilic organisms: Difference between revisions

Latest revision as of 14:36, 15 February 2022

Background

Bacteria that are particularly stimulated by excess iron

Microbiology

Bacteria
- Gram-positive
  - Listeria monocytogenes
  - Others: Bacillus, Clostridium, Corynebacterium, Erysipelothrix rhusiopathiae, Mycobacterium, Staphylococcus, Streptococcus, Gemella
- Gram-negative
  - Yersinia enterocolitica, in the context of iron chelation
  - Aeromonas hydrophilia
  - Escherichia coli
  - Vibrio vulnificus
  - Others: Acinetobacter, Alciligenes, Capnocytophaga canimorsus, Campylobacter, Chlamydia, Ehrlichia, Enterobacter, Klebsiella, Legionella, Moraxella, Neisseria, Pasteurella, Proteus, Pseudomonas, Plesiomonas, Shigella
Viruses: hepatitis B virus, hepatitis C virus, cytomegalovirus, parvovirus B19, HIV
Fungi
- Mucorales (particularly Rhizopus)
- Others: Candida, Cryptococcus, Histoplasma, Paracoccidioides, Trichosporon, Aspergillus, Pneumocystis jirovecii
Protozoa: Entamoeba histolytica, Leishmania, Naegleria fowleri, Plasmodium, Toxoplasma, Trypanosoma

Pathophysiology

Bacteria have a siderophore, that allows acquisition of iron from the environment
Yersinia does not have a siderophore, but has receptors for iron-bound exogenous siderophores such as deferoxamine

Risk Factors

Hemochromatosis

@@ Line 1: / Line 1: @@
-== Background ==
+==Background==
-* Bacteria that are particularly stimulated by excess iron
+*Bacteria that are particularly stimulated by excess iron
-=== Microbiology ===
+===Microbiology===
-* Bacteria
+*Bacteria
-** Gram-positive
+**Gram-positive
-*** [[Listeria monocytogenes]]
+***[[Listeria monocytogenes]]
-*** Others: [[Bacillus]], [[Clostridium]], [[Corynebacterium]], [[Erysipelothrix rhusiopathiae]], [[Mycobacterium species]], [[Staphylococcus species]], [[Streptococcus species]], [[Gemella]]
+***Others: [[Bacillus]], [[Clostridium]], [[Corynebacterium]], [[Erysipelothrix rhusiopathiae]], [[Mycobacterium]], [[Staphylococcus]], [[Streptococcus]], [[Gemella]]
-** Gram-negative
+**Gram-negative
-*** [[Yersinia enterocolitica]], in the context of iron chelation
+***[[Yersinia enterocolitica]], in the context of iron chelation
-*** [[Aeromonas hydrophilia]]
+***[[Aeromonas hydrophilia]]
-*** [[Escherichia coli]]
+***[[Escherichia coli]]
-*** [[Vibrio vulnificus]]
+***[[Vibrio vulnificus]]
-*** Others: [[Acinetobacter]], [[Alciligenes]], [[Capnocytophaga canimorsus]], [[Campylobacter]], [[Chlamydia]], [[Ehrlichia]], [[Enterobacter]], [[Klebsiella]], [[Legionella]], [[Moraxella]], [[Neisseria]], [[Pasteurella]], [[Proteus]], [[Pseudomonas]], [[Plesiomonas]], [[Shigella]]
+***Others: [[Acinetobacter]], [[Alciligenes]], [[Capnocytophaga canimorsus]], [[Campylobacter]], [[Chlamydia]], [[Ehrlichia]], [[Enterobacter]], [[Klebsiella]], [[Legionella]], [[Moraxella]], [[Neisseria]], [[Pasteurella]], [[Proteus]], [[Pseudomonas]], [[Plesiomonas]], [[Shigella]]
-* Viruses: [[hepatitis B virus]], [[hepatitis C virus]], [[cytomegalovirus]], [[parvovirus B19]], [[HIV]]
+*Viruses: [[hepatitis B virus]], [[hepatitis C virus]], [[cytomegalovirus]], [[parvovirus B19]], [[HIV]]
-* Fungi
+*Fungi
-** [[Mucorales]] (particularly [[Rhizopus]])
+**[[Mucorales]] (particularly [[Rhizopus]])
-** Others: [[Candida]], [[Cryptococcus]], [[Histoplasma]], [[Paracoccidioides]], [[Trichosporon]], [[Aspergillus]], [[Pneumocystis jirovecii]]
+**Others: [[Candida]], [[Cryptococcus]], [[Histoplasma]], [[Paracoccidioides]], [[Trichosporon]], [[Aspergillus]], [[Pneumocystis jirovecii]]
-* Protozoa: [[Entamoeba histolytica]], [[Leishmania]], [[Naegleria fowleri]], [[Plasmodium]], [[Toxoplasma]], [[Trypanosoma]]
+*Protozoa: [[Entamoeba histolytica]], [[Leishmania]], [[Naegleria fowleri]], [[Plasmodium]], [[Toxoplasma]], [[Trypanosoma]]
-=== Risk Factors ===
+=== Pathophysiology ===
+* Bacteria have a siderophore, that allows acquisition of iron from the environment
-* [[Hemochromatosis]]
+* [[Yersinia]] does not have a siderophore, but has receptors for iron-bound exogenous siderophores such as [[deferoxamine]]
+===Risk Factors===
+*[[Hemochromatosis]]
+[[Category:Infectious diseases]]