Ivermectin: Difference between revisions

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==Indications==
==Background==

===Indications===


*[[Strongyloides]]
*[[Strongyloides]]
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*Crusted [[scabies]]
*Crusted [[scabies]]


===Pharmacokinetics and Pharmacodynamics===
== Dose ==

*Does not cross blood-brain barrier

==Dosing==

*Usual dose is 150-200 mcg/kg PO or SC once


==Safety==
* Usual dose is 150-200 mcg/kg PO


== Adverse Effects ==
===Adverse Effects===


*Most common side effects are mild, including pruritus (25.3%), headache (13.9%), and dizziness (7.5%)
* Occasionally causes Mazzotti-type reaction in onchocerciasis, characterized by fever; pruritus, tender lymphadenopathy, arthralgias and myalgias
*Occasionally causes Mazzotti-type reaction in [[onchocerciasis]], characterized by fever, pruritus, tender lymphadenopathy, arthralgias and myalgias
* Rarely causes hypotension
*Rarely causes hypotension


[[Category:Antihelminthics]]
[[Category:Antihelminthics]]

Latest revision as of 18:23, 11 April 2021

Background

Indications

Pharmacokinetics and Pharmacodynamics

  • Does not cross blood-brain barrier

Dosing

  • Usual dose is 150-200 mcg/kg PO or SC once

Safety

Adverse Effects

  • Most common side effects are mild, including pruritus (25.3%), headache (13.9%), and dizziness (7.5%)
  • Occasionally causes Mazzotti-type reaction in onchocerciasis, characterized by fever, pruritus, tender lymphadenopathy, arthralgias and myalgias
  • Rarely causes hypotension