Ivermectin: Difference between revisions
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==Background== |
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===Indications=== |
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===Pharmacokinetics and Pharmacodynamics=== |
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*Does not cross blood-brain barrier |
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==Dosing== |
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*Usual dose is 150-200 mcg/kg PO or SC once |
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==Safety== |
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===Adverse Effects=== |
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*Most common side effects are mild, including pruritus (25.3%), headache (13.9%), and dizziness (7.5%) |
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*Occasionally causes Mazzotti-type reaction in [[onchocerciasis]], characterized by fever, pruritus, tender lymphadenopathy, arthralgias and myalgias |
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*Rarely causes hypotension |
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Latest revision as of 18:23, 11 April 2021
Background
Indications
Pharmacokinetics and Pharmacodynamics
- Does not cross blood-brain barrier
Dosing
- Usual dose is 150-200 mcg/kg PO or SC once
Safety
Adverse Effects
- Most common side effects are mild, including pruritus (25.3%), headache (13.9%), and dizziness (7.5%)
- Occasionally causes Mazzotti-type reaction in onchocerciasis, characterized by fever, pruritus, tender lymphadenopathy, arthralgias and myalgias
- Rarely causes hypotension
