Diabetic foot infection: Difference between revisions

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== Microbiology ==
== Background ==


===Microbiology===
* Typically involve a combination of ''Staphylococci'', ''Streptococci'', Proteobacteria (Gram-negative bacterial genus that includes enterics), and anaerobes
* Anaerobes are more likely to be involved in deeper, more chronic ulcers


*Typically polymicrobial, including:
== Further Reading ==
**[[Staphylococcus species]]
**[[Streptococcus species]]
**[[Proteobacteria]] (Gram-negative bacterial genus that includes enterics)
**[[Anaerobes]]
*Anaerobes are more likely to be involved in deeper, more chronic ulcers


== Management ==
* [https://doi.org/10.2337/db12-0771 The Neuropathic Diabetic Foot Ulcer Microbiome IsAssociated With Clinical Factors]. ''Diabetes''. 2013;62:923-930.

* Osteomyelitis
** Traditionally, 6 weeks of parenteral therapy
** May be able to shorten to 3 weeks based on more recent evidence[[CiteRef::gariani2020th]]

==Further Reading==

*[https://doi.org/10.2337/db12-0771 The Neuropathic Diabetic Foot Ulcer Microbiome IsAssociated With Clinical Factors]. ''Diabetes''. 2013;62:923-930.


[[Category:Skin and soft tissue infections]]
[[Category:Skin and soft tissue infections]]

Revision as of 19:22, 13 January 2021

Background

Microbiology

Management

  • Osteomyelitis
    • Traditionally, 6 weeks of parenteral therapy
    • May be able to shorten to 3 weeks based on more recent evidence1

Further Reading

References

  1. ^  Karim Gariani, Truong-Thanh Pham, Benjamin Kressmann, François R Jornayvaz, Giacomo Gastaldi, Dimitrios Stafylakis, Jacques Philippe, Benjamin A Lipsky, İlker Uçkay. Three versus six weeks of antibiotic therapy for diabetic foot osteomyelitis: A prospective, randomized, non-inferiority pilot trial. Clinical Infectious Diseases. 2020. doi:10.1093/cid/ciaa1758.