Genital ulcer disease: Difference between revisions
From IDWiki
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! colspan="5" |Painless |
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|[[Treponema pallidum pallidum]] |
|[[Treponema pallidum pallidum]] |
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|3-90 days |
|3-90 days |
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|[[penicillin]] 2.4 MU IM once |
|[[penicillin]] 2.4 MU IM once |
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|[[Chlamydia trachomatis]] serovars L1-L3 |
|[[Chlamydia trachomatis]] serovars L1-L3 |
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|3-30 days |
|3-30 days |
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|[[doxycycline]] 100 mg PO bid for 21 days |
|[[doxycycline]] 100 mg PO bid for 21 days |
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! colspan="5" |Painful |
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|[[acyclovir]] or [[valacyclovir]] for 5 to 10 days |
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|[[ciprofloxacin]] 500 mg PO once |
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|[[Klebsiella granulomatis]] |
|[[Klebsiella granulomatis]] |
Revision as of 16:14, 3 December 2020
Differential Diagnosis
Sexually-Transmitted Infections
Organism | Disease | % | Incubation | Treatment |
---|---|---|---|---|
Painless | ||||
Treponema pallidum pallidum | primary syphilis | 1% | 3-90 days | penicillin 2.4 MU IM once |
Chlamydia trachomatis serovars L1-L3 | lymphogranuloma venereum | <1% | 3-30 days | doxycycline 100 mg PO bid for 21 days |
Painful | ||||
Herpes simplex virus | genital herpes | 95% | 2-7 days (1º) | acyclovir or valacyclovir for 5 to 10 days |
Haemophilus ducreyi | chancroid | <1% | 5-14 days | ciprofloxacin 500 mg PO once |
Klebsiella granulomatis | donovanosis (granuloma inguinale) | <1% | 1-180 days | azithromycin 1 g PO weekly for 21 days (and healed) |
Other Infectious Causes
Non-Infectious Causes
- Bullous dermatoses
- Non-autoimmune
- Contact dermatitis
- Erythema multiforme (usually secondary to HSV)
- Toxic epidermolysis
- Autoimmune
- Non-autoimmune
- Non-bullous dermatoses
- Malignancy
- Trauma
- Idiopathic (12-51%)
Further Reading
- Management and treatment of specific syndromes – Genital Ulcer Disease (GUD). Canadian Guidelines on Sexually Transmitted Infections. 2016.