Prions: Difference between revisions
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Revision as of 01:51, 5 November 2020
Disease | Abbr | Host | Etiology |
---|---|---|---|
Animal Prion Diseases | |||
scrapie | — | sheep and goats | unknown origin |
transmissible mink encephalopathy | TME | mink | sheep or cattle origin |
chronic wasting disease | CWD | cervids | unknown origin |
bovine spongiform encephalopathy | BSE | cattle | unknown origin |
exotic ungulate spongiform encephalopathy | EUE | Nyala, Kudu | BSE origin |
feline spongiform encephalopathy | FSE | cats | BSE origin |
non-human primate spongiform encephalopathy | NHP | lemurs | BSE origin |
Human Prion Diseases | |||
Kuru | — | human | ritualistic cannibalism |
sporadic Creutzfeld-Jakob disease | sCJD | human | spontaneous mutation of PrPC to PrPSc |
familial Creutzfeld-Jakob disease | fCJD | human | mutations in PRNP gene |
Gerstmann-Straüssler-Scheinker syndrome | GSS | human | mutations in PRNP gene |
iatrogenic Creutzfeld-Jakob disease | iCJD | human | infection from surgical exposure to sCJD |
fatal familial insomnia | FFI | human | PRNP haplotype 178N-129M |
variant Creutzfeld-Jakob disease | vCJD | human | BSE origin |
sporadic fatal insomnia | sFI | human | spontaneous mutation of PrPC to PrPSc |
variably protease-sensitive prionopathy | VPSPr | human | spontaneous mutation of PrPC to PrPSc |