Eastern equine encephalitis virus: Difference between revisions

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== Background ==
==Background==


== Microbiology ==
===Microbiology===


* Virus in the [[Togaviridae]] family and [[Alphavirus]] genus
*Virus in the [[Family::Togaviridae]] family and [[Genus::Alphavirus]] genus


=== Epidemiology ===
===Epidemiology===


* Mosquito-borne avian infection carried by the [[Culiseta melanura]] mosquito
*Mosquito-borne avian infection carried by the [[Vector::Culiseta melanura]] mosquito
* Horses and humans are dead-end hosts, infected by bridge vectors including [[Aedes vexans]] and [[Coquillettidia perturbans]]
*Horses and humans are dead-end hosts, infected by bridge vectors including [[Vector::Aedes vexans]] and [[Vector::Coquillettidia perturbans]]
* Only one human case ever recorded in Ontario
*Usually only a handful of human cases annually in North America, and only one human case ever recorded in Ontario


== Clinical Manifestations ==
==Clinical Manifestations==


* Most are asymptomatic
*Most are asymptomatic
* Incubation period of [[Usual incubation period::4 to 10 days]]
*Incubation period of [[Usual incubation period::4 to 10 days]]
* For those who develop disease, it usually begins with an influenza-like illness, with fever, malaise, arthralgia, and myalgia, which lasts one to two weeks
*For those who develop disease, it usually begins with an influenza-like illness, with fever, malaise, arthralgia, and myalgia, which lasts one to two weeks
* Some people develop neurologic disease during the febrile illness, which may progress to encephalitis
*Some people develop neurologic disease during the febrile illness, which may progress to encephalitis
* There is a high mortality rate among those who develop [[encephalitis]], with death usually occuring between 2 and 10 days after illness onset
*There is a high mortality rate among those who develop [[encephalitis]], with death usually occuring between 2 and 10 days after illness onset
* It is possible to have permanent and severe neurologic sequelae
*It is possible to have permanent and severe neurologic sequelae


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Latest revision as of 12:05, 29 October 2020

Background

Microbiology

Epidemiology

  • Mosquito-borne avian infection carried by the Culiseta melanura mosquito
  • Horses and humans are dead-end hosts, infected by bridge vectors including Aedes vexans and Coquillettidia perturbans
  • Usually only a handful of human cases annually in North America, and only one human case ever recorded in Ontario

Clinical Manifestations

  • Most are asymptomatic
  • Incubation period of 4 to 10 days
  • For those who develop disease, it usually begins with an influenza-like illness, with fever, malaise, arthralgia, and myalgia, which lasts one to two weeks
  • Some people develop neurologic disease during the febrile illness, which may progress to encephalitis
  • There is a high mortality rate among those who develop encephalitis, with death usually occuring between 2 and 10 days after illness onset
  • It is possible to have permanent and severe neurologic sequelae