Cerebrospinal fluid leak: Difference between revisions

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==Background==
==Background==

* CSF leaks are associated with a high risk of meningitis (10-25%, depending on etiology and chronicity)
*CSF leaks are associated with a high risk of meningitis (10-25%, depending on etiology and chronicity)
*May be spontaneous, traumatic, or post-neurosurgical


==Management==
==Management==

* Current IDSA guidelines recommend:
*Current IDSA guidelines[[CiteRef::tunkel201720]] recommend:
** No routine prophylactic antibiotic in patients with basilar skull fractures and CSF leak
**No routine prophylactic antibiotic in patients with basilar skull fractures and CSF leak
** Surgical repair if leak lasts more than 7 days
**Surgical repair if leak lasts more than 7 days
** Pneumococcal vaccination
**Pneumococcal vaccination


==Further Reading==
==Further Reading==

* Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. ''Clin Infect Dis''. 2017;64(6):e34-e65. doi: [https://doi.org/10.1093/cid/ciw861 10.1093/cid/ciw861]
*Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. ''Clin Infect Dis''. 2017;64(6):e34-e65. doi: [https://doi.org/10.1093/cid/ciw861 10.1093/cid/ciw861]


[[Category:CNS infections]]
[[Category:CNS infections]]

Revision as of 23:41, 19 October 2020

Background

  • CSF leaks are associated with a high risk of meningitis (10-25%, depending on etiology and chronicity)
  • May be spontaneous, traumatic, or post-neurosurgical

Management

  • Current IDSA guidelines1 recommend:
    • No routine prophylactic antibiotic in patients with basilar skull fractures and CSF leak
    • Surgical repair if leak lasts more than 7 days
    • Pneumococcal vaccination

Further Reading

  • Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis. 2017;64(6):e34-e65. doi: 10.1093/cid/ciw861