Galactomannan: Difference between revisions

Revision as of 23:29, 21 September 2020

Quantitative analysis of galactomannan levels in either bronchoalveolar lavage or blood that is used to diagnose invasive aspergillosis

Galactomannan is a component of the cell wall of Aspergillus species that is released when the organism is actively dividing

Usual cuttoff is 0.5, but the higher it is, the more likely it is to be true positive
Bronchoalveolar lavage more sensitive than serum
False-positives in piperacillin-tazobactam, amoxicillin-clavulanic acid, Penicillium species (Talaromyces species), Histoplasma species, Fusarium species, Paecilomyces species

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-* Quantitative analysis of galactomannan levels in either bronchoalveolar lavage or blood that is used to diagnose invasive aspergillosis
+*Quantitative analysis of galactomannan levels in either bronchoalveolar lavage or blood that is used to diagnose invasive aspergillosis
-== Pathophysiology ==
+==Pathophysiology==
-* Galactomannan is a component of the cell wall of ''Aspergillus'' species that is released when the organism is actively dividing
+*Galactomannan is a component of the cell wall of [[Aspergillus species]] that is released when the organism is actively dividing
-== Interpretation ==
+==Interpretation==
+*Usual cuttoff is 0.5, but the higher it is, the more likely it is to be true positive
-* Bronchoalveolar lavage more sensitive than serum
+*Bronchoalveolar lavage more sensitive than serum
-* False-positives in pip/tazo, amox/clav, Penicillium spp., Histoplasma spp.
+*False-positives in [[piperacillin-tazobactam]], [[amoxicillin-clavulanic acid]], [[Penicillium species]] ([[Talaromyces species]]), [[Histoplasma species]], [[Fusarium species]], [[Paecilomyces species]]
 [[Category:Diagnostics]]