Congenital HSV: Difference between revisions

Latest revision as of 16:22, 20 September 2020

Occurs in children born to mothers who had primary HSV-1 or HSV-2 during pregnancy

Characterized by microcephaly, hydrocephalus, chorioretinitis, and skin findings
- Rash may be vesicular, bullous, or cicatricial
- Rash either present at birth or within a few days
- Two thirds have severe CNS involvement

Most commonly made with PCR of lesions or CSF
- Do not send superficial swabs for PCR during the first 24 hours of life, since this can generate false positive from superficial contamination from the birthing process

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+== Background ==
-* Occurs in children born to mothers who had primary [[HSV-1]] or [[HSV-2]] during pregnancy
-* Characterized by [[Causes::microcephaly]], [[Causes::hydrocephalus]], [[Causes::chorioretinitis]], and skin findings
-** Rash may be vesicular, bullous, or cicatricial
-** Rash either present at birth or within a few days
-** Two thirds have severe CNS involvement
+*Occurs in children born to mothers who had primary [[HSV-1]] or [[HSV-2]] during pregnancy
-[[Category:Pediatrics]]
-[[Category:Viruses]]
+== Clinical Manifestations ==
-[[Category:Infectious diseases]]
+*Characterized by [[Causes::microcephaly]], [[Causes::hydrocephalus]], [[Causes::chorioretinitis]], and skin findings
+**Rash may be vesicular, bullous, or cicatricial
+**Rash either present at birth or within a few days
+**Two thirds have severe CNS involvement
+== Diagnosis ==
+* Most commonly made with PCR of lesions or CSF
+** Do not send superficial swabs for PCR during the first 24 hours of life, since this can generate false positive from superficial contamination from the birthing process
+[[Category:Congenital infections]]