Imipenem-relebactam: Difference between revisions
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==Background== |
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===Mechanism of Action=== |
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*Relebactam improves activity against beta-lactamases including class A and C |
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*Also includes cilastatin, as per usual with imipenem |
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===Spectrum of Activity=== |
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*Active against Enterobacterales including ESBL, AmpC, and KPC, Bacteroides, MDR Pseudomonas |
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*No activity against many Gram-positives or afermentative Gram-negatives |
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Revision as of 14:01, 26 August 2020
Background
Mechanism of Action
- Relebactam improves activity against beta-lactamases including class A and C
- Also includes cilastatin, as per usual with imipenem
Spectrum of Activity
- Active against Enterobacterales including ESBL, AmpC, and KPC, Bacteroides, MDR Pseudomonas
- No activity against many Gram-positives or afermentative Gram-negatives
